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  • 1
    Electronic Resource
    Electronic Resource
    In Vitro and In Vivo Behaviour of Bioactive Glass Composites Bearing a NSAID (2003)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 254-256 (Dec. 2003), p. 177-180 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/47/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.254-256.177.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Prenatal intramedullary gliofibroma (1984)
    Springer
    Acta neuropathologica 62 (1984), S. 230-234 
    Details
    ISSN: 1432-0533
    Keywords: Gliofibroma ; Prenatal glioma ; Spinalcord tumor ; Desmoplasia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of an unusual congenital intramedullary tumor of the spinal cord is reported. A paraplegic 11-day-old boy with hypotonia and atrophy of the abdominal and lower-extremity muscles showed a complete myelographic block between T-5 and T-8. Surgical exploration disclosed an elongated tumor mass within the spinal cord, that blended with the surrounding nervous-system tissue. Light and electron microscopy showed that the tumor was composed of intermingled well differentiated astrocytes and fibroblasts. These two cell types often were surrounded by the same basal lamina. There were no intercellular junctions. Gliofibrils were abundant, and the interstitial spaces contained abundant collagen and reticulin fibers There were no histological signs of malignancy. We conclude that this is a case of prenatally arising gliofibroma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691857
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Untoward effects of pharmacological doses of insulin in early chick embryos: through which receptor are they mediated? (1985)
    Springer
    Diabetologia 28 (1985), S. 308-313 
    Details
    ISSN: 1432-0428
    Keywords: Insulin ; proinsulin ; insulin-like growth factors ; multiplication-stimulating activity ; insulin effects on growth ; embryogenesis ; chick embryo
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The teratogenic effect of insulin in early vertebrate embryos is controversial and the mechanisms involved are unknown. We studied the effects of pharmacological doses of insulin in chick embryos during the period of differentiation. We compared the effects of insulin with two proinsulins, desoctapeptide-insulin and multiplication-stimulating activity, peptides that have little insulin-like metabolic activity while they have significant growth effects. Chick embryos at 46 h of development were injected with the different peptides. At 96 h the mortality and abnormal growth elicited by the peptides were dose-dependent. Considering the indices of lethality (LD50) and affected embryos (ED50) as 100% for insulin, proinsulin was 59–66% as potent as insulin, desoctapeptide-insulin 2–6% and multiplication-stimulating activity 176–204%. In the surviving embryos, insulin (5 μg, decreased DNA, RNA and protein content by 49%, 40% and 48% respectively compared with controls. The effects of insulin were not corrected by simultaneous glucose injections. These data suggest that insulin, at pharmacological doses, interferes with embryo development through a non-metabolic pathway, probably via a growth-type receptor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271691
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  • 4
    Electronic Resource
    Electronic Resource
    Morphology of cochlear root neurons in the rat (1988)
    Springer
    Journal of neurocytology 17 (1988), S. 711-725 
    Details
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The morphology of large neurons in the cochlear nerve root of albino rat has been studied with a variety of techniques including Nissl and cell-myelin staining, Golgi impregnation, horseradish peroxidase back-filling of severed axons, transmission electron microscopy, and morphometry. The cells, called root neurons, resemble the globular cells of the ventral cochlear nucleus in having an oval cell body, an eccentric nucleus, an axon that projects centrally via the trapezoid body, and in receiving many primary-like axosomatic boutons. The root neurons, however, are larger than globular cells, and they have at least two types of dendrites oriented, respectively, parallel and across the cochlear nerve fibres. The soma, moreover, has less finely dispersed Nissl material, is less completely covered with terminals, and receives a smaller proportion of presumably inhibitory synapses. So far, this particular type of neuron has been observed only in rat and mouse.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01260998
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