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  • 1
    Electronic Resource
    Electronic Resource
    Sweet syndrome in multiple myeloma: a series of six cases (2003)
    Oxford, UK : Munksgaard International Publishers
    Journal of cutaneous pathology 30 (2003), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Sweet syndrome (SS), a paraneoplastic syndrome characterized by fever, neutrophilia, multiple erythematous painful plaques, and a dense dermal neutrophilic infiltration, has a known association with hematologic malignancies such as acute myelogenous leukemia. However, no clear association with multiple myeloma (MM) has been reported.Materials and methods:  Pathology reports of the 2357 patients with multiple myeloma at the University of Arkansas for Medical Sciences were reviewed to retrieve cases who had developed SS. Cytogenetic studies and immunoglobulin secretory status were retrieved. Five cases of SS in MM and 25 cases of SS in patients without MM underwent syndecan-1 immunohistochemistry.Observations:  Six cases of SS occurring in the setting of MM showed a predominance in patients secreting IgG paraprotein. Five of the six patients received granulocyte-colony stimulating factor while the sixth received granulocyte-monocyte-colony stimulating factor. Fifty percent showed a non-specific cytogenetic anomaly.Conclusions:  There is no specific cytogenetic anomaly associated with SS in the setting of MM. This paraneoplastic syndrome may be secondary to elevated levels of granulocyte colony stimulating factor (G-CSF), possibly with a component of enhanced sensitivity to endogenous G-CSF. The immunoglobulin secretory status parallels that seen in MM with cutaneous involvement, but IgG secretors may be at an increased risk of developing SS compared with their counterparts who secrete other immunoglobulins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0303-6987.2002.029.x
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  • 2
    Electronic Resource
    Electronic Resource
    The process of epithelial cell attachment to glass surfaces studied by reflexion contrast microscopy
    Amsterdam : Elsevier
    Experimental Cell Research 118 (1979), S. 414-418 
    Details
    ISSN: 0014-4827
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0014-4827(79)90169-1
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  • 3
    Electronic Resource
    Electronic Resource
    AIDS in the human brain (1986)
    [s.l.] : Nature Publishing Group
    Nature 319 (1986), S. 8-8 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE causative agent of acquired immune deficiency syndrome or AIDS (variously known as LAV, HTLV-III or ARV virus) is akin to the lentiviruses1. It would appear, on current estimates of AIDS virus prevalence in the US population (about 0-5 per cent), that between 105 and 106 persons may develop ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/319008a0
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  • 4
    Electronic Resource
    Electronic Resource
    HIV in infected lymph nodes (1994)
    [s.l.] : Nature Publishing Group
    Nature 370 (1994), S. 256-256 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR - To answer questions raised by Duesberg1, and in a separate and scientific sense by Phillips et al.2, concerning the quantities of HIV RNA (detected by in situ hybridization) contained in the ger-minal centres of lymph nodes of HIV-infected individuals, we have constructed a test object ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/370256a0
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  • 5
    Electronic Resource
    Electronic Resource
    In situ hybridization in HIV research (1993)
    New York, NY [u.a.] : Wiley-Blackwell
    Microscopy Research and Technique 25 (1993), S. 78-84 
    Details
    ISSN: 1059-910X
    Keywords: Lentivirus ; HIV ; AIDS ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: In situ hybridization (ISH) for HIV is an arduous, demanding means of detecting viral genetic material in cells and tissues. Good ISH requires broad technical skills and devotion to controls for every step of the process as well as a critical eye when interpreting results. ISH may be used to detect HIV in three ways: by hybridizing to viral RNA, by hybridizing to proviral mRNA being produced for virion packaging, and by hybridizing to proviral DNA in the cytoplasm or integrated in the nucleus of an infected cell. Here we discuss the technical considerations involved and the problems encountered in using ISH to study the pathobiology of HIV infection. Published 1993 Wiley-Liss, Inc.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jemt.1070250111
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