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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 5 (1981), S. 341-348 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les principes de traitement de la pancréatite aigüe dépendent de la gravité de la maladie et de ses complications. Comme cellesci peuvent apparaître n'importe quand, le malade doit être placé dans une unité de soins intensifs pour surveillance constante et appréciation continue de la gravité de son état. Il doit rester dans cette unité pendant les 48 premières heures au moins, même s'il n'a aucun signe de choc. La seule exception à cette règle peut être la pancréatite bénigne sans signe de péritonite. Le traitement de base doit comporter des antalgiques, un jeûne absolu, l'aspiration gastrique, des antibiotiques, le remplacement par voie parentérale de l'eau, des électrolytes, de l'albumine et du sang. Toute hyperglycémie doit être corrigée. Il faut administrer de l'héparine s'il y a coagulation intravasculaire disséminée. La dialyse péritonéale est importante en cas d'insuffisance rénale. Toute complication pulmonaire exige de l'oxygène humidifié ou un respirateur avec PEEP. L'effet bénéfique de la dialyse péritonéale n'a été démontré que chez l'animal et dans des études rétrospectives chez l'homme; il faut cependant la recommander en cas de choc grave et pour corriger les désordres électrolytiques s'il y a de l'ascite, même avant que ne survienne l'anurie.
    Notes: Abstract Therapeutic measurements for acute pancreatitis depend on the severity of the disease and its complications. Since complications of acute pancreatitis may develop at any time, patients should be admitted to an intensive care unit for assessment (and frequent reassessment) of the severity of the disease and of the development of complications; they should remain in the intensive care unit for the first 48 hours at least, even if no signs of shock are apparent. The only exceptions to this rule are mild cases without signs of peritonitis. Basic therapy should include relief of pain, total fasting, nasogastric suction, parenteral replacement of fluids, electrolyte, albumin, and blood, and antibiotics. Hyperglycemia should be corrected and heparin should be given in cases of disseminated intravascular coagulation. In renal insufficiency, peritoneal dialysis is important, and in respiratory complications, humidified oxygen or artificial ventilation including positive end expiratory pressure therapy should be applied. Although the effect of peritoneal dialysis has been proven only in animal experiments and in retrospective studies in man, it is recommended in severe cases for shock therapy and for correction of electrolyte imbalance when ascites is present, even before anuria occurs.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 20 (1996), S. 126-131 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Historically, carcinoids have long been known to be a morphologically distinct class of rare intestinal tumors that behave less aggressively than the more common intestinal adenocarcinomas. It was not until much later that their endocrine nature was recognized. Some authors restrict the term carcinoid to intestinal endocrine tumors, whereas others include a large variety of neuroendocrine tumors. In the WHO classification of 1980, carcinoids were defined as tumors of the diffuse neuroendocrine system that are either benign or neoplasms with a more favored prognosis than carcinomas. They are characterized by a typical growth pattern, silver affinity, and positive immunohistochemical reaction with neuron-specific markers; and they can express different peptides and biogenic amines. Neuroendocrine tumors originating from endocrine glands (pituitary, thyroid, adrenals, pancreas) and highly malignant neuroendocrine carcinomas are excluded from the carcinoid group of neoplasms. For the natural history of carcinoid tumors several independent predictive parameters can be defined: size, site of origin, growth pattern, and hormone dependence. The number of neuropeptides and amines expressed by a carcinoid or the amount of biologically active neurohormones secreted are of no prognostic significance regarding malignant behavior. The carcinoid syndrome is a rare clinical entity that occurs with a prevalence of 1.6% for carcinoid tumors and almost only if liver metastases are present. The complex clinical symptoms are only partially explained by the secretion of serotonin and tachykinins.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 27 (1949), S. 268-271 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 32 (1954), S. 819-820 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 32 (1954), S. 1003-1004 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassend ergibt sich, daß beim Thymusinvolutions-Test keine Inaktivierung des ACTH durch Heparin nachzuweisen ist. Heparin führt vielmehr zu einer signifikanten Thymusverkleinerung und verstärkt die ACTH-Wirkung auf den Thymus. Eine ACTH-ähnliche Wirkung des Heparin ist damit jedoch nicht bewiesen, weil die Nebennieren anscheinend nicht mitreagieren.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 33 (1955), S. 43-44 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Diabetologia 27 (1984), S. 484-485 
    ISSN: 1432-0428
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 222 (1954), S. 487-512 
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Bei der experimentellen Pankreatitis der Ratte durch Injektion von Natriumtaurocholat, Trypsin oder Enterokinase kommt es trotz schwerer morphologischer Veränderungen nicht zu einer nachweisbaren Aktivierung von Trypsin oder proteolytischen Enzymen. Der Zymogengehalt ist unverändert. 2. Bereits 15 min nach Injektion von Trypsin in den Pankreasgang ist im Homogenat kein aktives Trypsin mehr nachzuweisen. Entsprechende Trypsinzusätze zum calciumhaltigen Homogenatansatz in vitro führen dagegen zu einer starken Trypsinogenaktivierung. 3. Eine günstige Wirkung auf Verlauf, pathologisch-anatomische Befunde und Blutamylasewerte durch 1–3malige intravenöse Injektion von 2 bis 60 000 KI.E. Trasylol ließ sich bei der experimentellen Pankreatitis der Ratte nicht nachweisen. Bei sehr hohen Dosen von Trasylol (ab 30 000 KI.E.), die von normalen Ratten gut toleriert werden, stieg die Mortalität der Pankreatitis sogar signifikant an.
    Type of Medium: Electronic Resource
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