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Digitale Medien

Cardiac myxomas: Immunohistochemical study of benign and malignant variants (1991)

Curschellas, E. ; Toia, D. ; Borner, M. ; [weitere]

Springer

Virchows Archiv 418 (1991), S. 485-491

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Details

ISSN: 1432-2307

Schlagwort(e): Cardiac myxoma ; Immunohistochemistry ; Histogenesis

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Immunohistochemical investigation of 11 cardiac myxomas (CMs) including one malignant metastasizing CM showed a co-expression of epithelial (lu-5 and CAM 5.2), mesenchymal (vimentin) and neuroendocrine antigens (neuron-specific enolase) in all tumour cells. Factor VIII was found in the endothelial cells of capillaries only. In the subendocardium of fetal heart tissue close to the foramen ovale myofibroblasts reacting with the panepithelial antibody lu-5 were detected. We conclude that CMs are neoplasms that may develop from embryonic cell remnants.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01606497

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