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  • 1
    ISSN: 1432-1076
    Keywords: Exercise testing ; Congenital heart disease ; Acrobic capacity ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aerobic capacity of patients with different forms of congenital heart disease was serially evaluated in 79 patients and the evolution was correlated with the lesion and the level of daily activity. The patients were divided into six groups: patients with a small ventricular septal defect (VSD) with mini shunt (n=14), mild pulmonary valve stenosis with gradient 〈40 mm Hg (PS) (n=12), mild to moderate aortic valve stenosis (gradient 36±17 mm Hg) (AS) (n=12), patients 4.7±2.1 years after repair of tetralogy of Fallot (PO-TF) (n=16), patients 2.2±2.9 years after closure of a high flow/high gradient VSD (PO-VSD) (n=13), and patients 2.6±1.7 years after Fontan repair (Fontan-PO) (n=12). Aerobic capacity was assessed by determination of the ventilatory anaerobic threshold (VAT). VAT reflects the highest aerobic exercise level prior to a disproportionate increase of CO2 and ventilation relative to O2 uptake; it is independent of patient motivation. Data are expressed as percentage of normal O2 uptake at VAT, determined in 234 age/gender matched controls. The habitual level of physical activity was assessed by a standardised questionnaire. Aerobic capacity in all subgroups of patients, even with very mild defects, was at or below the lower limit of normal. Children left unrestricted from physical exercise (VSD, PS, PO-VSD) had no change over the study period. However, aerobic capacity of patients with medically imposed physical restrictions (AS) and significant residual haemodynamic lesions (PO-TF, Fontan) decreased with age. In patients with AS, PO-TF and Fontan-PO the habitual level of physical activity was significantly decreased compared to controls. Conclusion Cardiovascular exercise performance in children with medically imposed restriction of intensive physical exercise (AS) or residual haemodynamic lesions (TF and Fontan-PO) declines progressively during medium-term follow up. In the other patient groups (VSD, PS, VSD-PO), exercise performance remains stable.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1076
    Keywords: Key words Complete congenital heart block Fetal hydrops ; Neonatal pacing ; Epicardial pacing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The management of the preterm fetus with hydrops due to complete congenital heart block is difficult. The outcome is frequently associated with significant morbidity and mortality. Two fetuses presented at the post menstrual age of 29 and 30 weeks respectively with severe hydrops due to complete heart block. The following staged approach was adopted: (1) enhance fetal lung maturation with maternal corticosteroids and thyroid releasing hormone for 48 h; (2) elective Caesarean section; (3) classical neonatal management consisting of intubation and ventilation, drainage of all cavities with effusions; (4) increase neonatal heart rate by administration of IV isoprenaline, by bipolar trans-oesophageal pacing or epicutaneo-oesophageal pacing; (5) after the regression of the hydrops, start epicardial pacing after implantation of 2 or 3 temporary epicardial 3/0 pacemaker; (6) implantation of a permanent abdominal pacing system with steroid epicardial tip once the threshold exceeds 20 mA or when the baby weighs more than 1500 g. In these patients a permanent pacing system was implanted at the ages of 8 weeks (2045 g) and 4 weeks (1560 g) respectively. No major complications occurred; the cardiac outcome with 37 and 34 months of follow up is excellent. Conclusion This proposed staged approach with tem‐porary epicardial leads can improve the outcome of hydropic fetuses due to complete congenital AV block.
    Type of Medium: Electronic Resource
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