ISSN:
1434-193X
Schlagwort(e):
Enzymes
;
Kinetic resolution
;
Sulfoxides
;
Chiral resolution
;
Hydrolyses
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Selected racemic trans-2-alkoxycarbonyl-3,6-dihydro-2H-thiopyran S-oxides 2a-h have been subjected to enzyme-assisted hydrolysis under conditions of kinetic resolution to give the corresponding acids and recovered esters with moderate to high enantiomeric purities (up to 95%). The enantioselectivity of the reaction was found to be strongly dependent on the structures of the substrates used.
Zusätzliches Material:
3 Ill.
Materialart:
Digitale Medien
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