ISSN:
1749-6632
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Natural Sciences in General
Notes:
In a recent study of the effects of various forms of therapy given during the first 48 hr to patients with burns, colloidal solutions were shown to be more effective in maintaining blood volume levels than only hypotonic saline solutions (Davies, 1964). Since these patients also received different amounts of sodium, the question whether the different inputs of sodium may have modified the changes in blood volume was left open.This study attempts an assessment of the effects of differing inputs of sodium upon blood volume levels. A direct comparison has been made between the blood volume levels in patients given equal volumes of either hypotonic bicarbonate saline or isotonic lactate saline. A more complex comparison has been devised for patients with burns of more than 40% of the body surface since they were also given varying volumes of colloid–usually reconstituted freeze-dried plasma.Since all these forms of therapy result in substantial intakes of sodium, a study has also been made of some of the effects of these large intakes using two radioactive isotopes of sodium. Measurements have been made of the biological half-life of sodium, its total exchangeable content, the dilution volume of sodium, and the amounts of sodium lost in urine and exudate.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1749-6632.1968.tb14718.x
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