ISSN:
1569-8041
Keywords:
chemotherapy
;
high-dose chemotherapy
;
PPNET
;
stem cell transplantation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We describe a 42-year-old male patient with a primitive peripheralneuroectodermal tumor (PPNET) arising from the kidney. The patient was treatedsequentially with surgery, radiotherapy, experimental cytokine treatment(rhIL-6), combination chemotherapy and consolidated in complete remission withhigh-dose chemotherapy, supported by autologous stem cells (AST) andhematopoietic growth factors. The patient remains in complete remission at 34+months after AST and is surviving disease-free for five years after initialpresentation. The case presented here is unusual because of the renal origin and the longremission duration and survival when compared with the usual outcome of adultmetastatic PPNET. High-dose chemotherapy may have favorably influenced the outcome in thispatient. The case is discussed in the context of the general treatment ofmetastatic PPNET.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008271903643
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