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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Child 14 (1988), S. 0 
    ISSN: 1365-2214
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Summary Over a 4-year period a significant fall occurred in the mean birthweight and mean gestational age of prematurely born children who subsequently developed spastic diplegia. This coincided with a considerable improvement in perinatal mortality in the unit in which they were delivered. However, although the number of premature deliveries remained stable, the disorder did not become less common. No specific aetiological factors were identified, but the 24 affected children frequently had a history of adverse prenatal or perinatal factors. We conclude that high standards of obstetric and neonatal care prevent the subsequent development of spastic diplegia in low birthweight infants. However, these factors have also improved the survival of very low birthweight infants who have a much higher risk for the disorder and this has prevented a significant reduction in its frequency.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Child 19 (1993), S. 0 
    ISSN: 1365-2214
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Summary All surviving infants with birthweight ≤ 1500 g born in 1982 and 1983 at St. James's University Hospital, Leeds, were followed up for 5 years. There were 88 survivors (including 5 in utero transfers) from the original cohort of 126 infants. In their fifth year the following assessments were made; neurological, audiological, intellectual, behavioural, growth and general health. A comparison group of full-term male infants was also studied with respect to intellectual status, social and emotional behaviour and general health.Principal neurological impairments found were: cerebral palsy 9 (10·2%), hydrocephalus 1 (1·1%), epilepsy 2 (2·3%) and sensorineural deafness 2 (2·3%). One third of the VLBW children required the services of the child development centre. Seventy-nine of the 88 VLBW children were tested with the WPPSL Seven (8·8%) scored below 70. The VLBW boys had mean IQ scores of 90·6 while the mean for the girls was 100–2. The very low birthweight boys were significantly intellectually impaired compared with their peers.Socially and emotionally they were largely comparable with their full-term peers. The findings suggest that there has been no increase in severe disability following a policy of active neonatal intensive care. However, the quality of survival of VLBW children born in the 1980s, despite improvements care perinatal care, remains a major concern.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Neural computing & applications 3 (1995), S. 234-241 
    ISSN: 1433-3058
    Keywords: Ambiguous inputs ; Neural network ; Performance metric ; Post-processing ; Pre-processing ; Threshold
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract The development of a feed-forward neural network to predict attendance and non-attendance at a hospital outpatient clinic is described. Particular emphasis is given to the post-processing applied to the network output, and to the choice of information presented to the network. The effect of individual inputs on the performance of the network is examined, and two methods of dealing with the problem of ambiguous input data are explored. It is shown that good results (approximately 90% accuracy) are achieved with a feedforward network — having 15 input nodes, a single hidden layer of five nodes and one output node with supervised backpropagation — even where data is limited, and that an understanding of the problem can lead to the modification of standard procedures and improved network performance.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1433-3058
    Keywords: High risk pregnancy ; Logistic regression ; Neural networks ; Pre-term delivery ; Receiver Operating Characteristic curve
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract The aim of this study was to produce models for the prediction of high risk pregnancies, with particular emphasis on pre-term delivery. Neural network and logistic regression models have been developed utilising pregnancy and delivery data spanning a period of seven years. Five input factors were used as explanatory variables: age, number of previous still births, gestational age at first clinical assessment, diabetes and a measure of socio-economic status. There was little difference between average model performance for the two techniques: optimal neural network performance was achieved with a fully connected feed forward network comprising a single hidden layer of three nodes and single output node. This produced a Receiver Operating Characteristic (ROC) curve area of 0.700. The ROC area for logistic regression models was 0.695. The performance of these models reflected weak associations within the data. However, performance is encouraging given the relatively limited number of predictive inputs.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inherited metabolic disease 16 (1993), S. 1051-1052 
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inherited metabolic disease 7 (1984), S. 85-85 
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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