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  • 1
    Electronic Resource
    Electronic Resource
    Myocardial infarct sizing and assessment of reperfusion by magnetic resonance imaging: a review (1991)
    Springer
    The international journal of cardiovascular imaging 7 (1991), S. 133-138 
    Details
    ISSN: 1573-0743
    Keywords: Gadolinium ; Myocardium ; Magnetic Resonance Imaging ; Contrast enhancement ; Reperfusion therapy ; Infarct Sizing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Early thrombolytic therapy restores patency of thrombotic coronary artery occlusion in many patients. Intravenous streptokinase appears to be effective in achieving recanalization of the occluded infarct-related artery, thereby reducing myocardial infarct size. However, it may be difficult to assess non-invasively the relative value of different reperfusion therapies. MR imaging with or without the use of contrast agents may become a reliable non-invasive technique to assess infarct size after reperfusion therapy. There are indications that early MR imaging after administration of Gd-DTPA is able to differentiate reperfused from non-reperfused infarcts. Furthermore, MR infarct sizing using Gd-DTPA can demonstrate infarct size reduction in patients with successful reperfusion. The availability of ultrafast imaging methods and MR contrast agents may allow assessment of myocardial perfusion in the near future. This article reviews the current status of MR imaging for evaluating ischemic myocardial disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01798054
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Improved detection of acute myocardial infarction by magnetic resonance imaging using Gadolinium-DTPA (1989)
    Springer
    The international journal of cardiovascular imaging 5 (1989), S. 1-8 
    Details
    ISSN: 1573-0743
    Keywords: Magnetic Resonance Imaging ; acute myocardial infarction ; Gadolinium-DPTA ; contrast agents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To assess the value of the paramagnetic contrast agent Gadolinium (Gd)-DTPA in Magnetic Resonance Imaging (MRI) of acute myocardial infarction (AMI), we studied 20 patients with a first AMI by ECG-gated MRI before and after intravenous administration of 0.15mmol/kg Gd-DTPA. The MRI studies were performed after a mean of 98 hours (range 15–241) after the acute onset of AMI. Spin-echo measurements (TE 30 msec) were made using a Philips Gyroscan (0.5 Tesla). After performing the baseline MRI scans, the MRI procedure was repeated every 10 minutes for up to 40 minutes following injection of Gd-DTPA. In 18 (90%) patients contrast enhancement in the infarcted myocardial areas was observed after Gd-DTPA. In these patients intensity versus region curves, derived from 9 to 11 adjacent myocardial regions of interest, showed increased signal intensities in the infarcted areas after administration of Gd-DTPA. The precontrast signal intensity ratio between infarcted and normal myocardium was 1.14±0.15 (mean±SD); the postcontrast ratios at 10 minutes were 1.41±0.21 (P 〈0.05), at 20 minutes 1.61±0.19 (P 〈0.01), at 30 minutes 1.43±0.20 (P 〈 0.05), and at 40 minutes 1.33±0.20 (P=NS). It is concluded that MRI using the contrast agent Gd-DTPA significantly improves the visualization and detection of infarcted myocardial areas in patients with AMI and that optimal contrast enhancement is obtained 20 minutes after administration of Gd-DTPA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01745226
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Imaging of recurrent ventricular septal defect and supravalvular pulmonary stenosis eight years after assumed total surgical repair of tetralogy of Fallot (1996)
    Springer
    The international journal of cardiovascular imaging 12 (1996), S. 79-83 
    Details
    ISSN: 1573-0743
    Keywords: tetralogy of Fallot ; congenital heart disease ; echocardiography ; magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 42-year-old man underwent assumed total surgical repair of an acyanotic tetralogy of Fallot: a perimembranous ventricular septal defect (VSD) was closed with a dacron patch and myectomy of the infundibulum of the right ventricular outflow tract was performed. Reexamination eight years later revealed a large recurrent VSD and by surprise a narrow supravalvular ridge above rudimentary pulmonary cusps in the pulmonary trunk, leading to a pressure drop of 70 mmHg across the supravalvular stenosis. The latter finding was not recognized during the operation eight years before. The diagnosis could noninvasively be established by means of magnetic resonance imaging. During revision surgery the VSD was closed and an aortic homograft was inserted as conduit between the right ventricle and the pulmonary artery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01880737
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Assessment of left ventricular volume and mass by cine magnetic resonance imaging in patients with anterior myocardial infarction intra-observer and inter-observer variability on contour detection (1996)
    Springer
    The international journal of cardiovascular imaging 12 (1996), S. 11-19 
    Details
    ISSN: 1573-0743
    Keywords: image processing ; left ventricle ; left ventricular mass ; left ventricular volume ; magnetic resonance imaging ; myocardial infarction ; observer variability ; remodeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Remodeling of the left ventricle after myocardial infarction can be documented by calculation of left ventricular volume and mass, using endocardial and epicardial tracings of multilevel multiphase short-axis cine magnetic resonance (MR) imaging series. We assessed left ventricular volume and mass from 8 slices and during 12 phases of the cardiac cycle in seven patients with an anterior wall myocardial infarction; one patient was studied twice, leaving eight MR examinations to be evaluated. Purpose of this study was to assess the intra-observer and interobserver variability of epicardial volume, endocardial volume, and left ventricular mass from contours manually traced by two independent observers. For the eight MR examinations, epicardial volume was found to be 292 ± 51 ml (mean ± SD) at end-diastole, which decreased to 237 ± 55 ml at end-systole. Endocardial volume was 141 ± 31 ml at end-diastole, which decreased to 79 ± 27 ml at end-systole. Left ventricular ejection fraction was 45 ± 8%. Mean left ventricular mass, when averaged over all patient studies and all phases, was 159 ± 30 g. Intra-observer and inter-observer variability were found to be 3.5% and 5.2% for endocardial volume, 2.0% and 2.5% for epicardial volume, and 3.6% and 3.6% for left ventricular mass, respectively. The contour analysis showed a statistically significant phase effect in the endocardial contour in the midventricular slices, which was resolved after establishing a more precise definition for the tracing of the endocardial border. In conclusion, left ventricular volume and mass in patients with an anterior wall myocardial infarction can be assessed with high reproducibility and relibility from manual contour tracings. A precise protocol for the definition of endocardial and epicardial contours is required to obtain reproducible and reliable results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01798113
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    Paper (German National Licenses)
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