ISSN:
1573-4986
Keywords:
β-mannosidosis
;
carbohydrate-urea conjugate
;
NMR spectroscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A previously unknown substance, mannosyl-β(1–4)-N-acetylglucosaminyl-β(1-N)-urea, has been isolated from the urine of patients with β-mannosidosis in addition to the main metabolite mannosyl-β(1–4)-N-acetylglucosamine. Structural investigation was carried out by fast atom bombardment mass spectrometry and high-resolution1H-nuclear magnetic resonance spectroscopy at 500 MHz. It was postulated that the occurrence of this carbohydrate-urea conjugate in urine results mainly from urine handling.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01049082
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