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The lasting qualities of PERT: Preferences and perceptions of R&D project managers (1984)

Dougherty, D. M. ; Stephens, D. B. ; Ezell, D. E.

Oxford, UK : Blackwell Publishing Ltd

R & D management 14 (1984), S. 0

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ISSN: 1467-9310

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Economics

Notes: This survey was conducted on the perceived popularity of PERT and PERT-type management systems; whether PERT'S applications were static, increasing, or decreasing, and whether its use was by choice or imposition. The extent of applications of PERT for managing various types of research and development (R&D) was examined with the view to ascertaining its individual popularity when applied to (a) basic research, (b) applied research, or (c) development projects. In addition, an inquiry was made into the estimated expense of PERT systems to plan and control projects as a percentage of the budget. The results of the survey are presented and discussed relative to various sizes of R&D organizations.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1467-9310.1984.tb00507.x

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Tryptophan depletion and aggressive responding in healthy males (1996)

Moeller, F. G. ; Dougherty, D. M. ; Swann, A. C. ; [et al.]

Springer

Psychopharmacology 126 (1996), S. 97-103

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ISSN: 1432-2072

Keywords: Serotonin ; Tryptophan ; Aggression

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract In order to study the effect of decreasing plasma tryptophan levels on aggressive responding in a controlled laboratory setting, we administered two doses (25 g and 100 g) of a tryptophan-free amino acid mixture to ten healthy male subjects after 24 h of a low tryptophan diet. Subjects were screened for current or past psychiatric, or non-psychiatric medical illness. Aggressive responding on a free-operant laboratory measure of aggression (the Point Subtraction Aggression Paradigm) and plasma tryptophan levels were measured before and after drinking the amino acid mixture. There was a significant increase in aggressive responding 5 h after the 100 g mixture and a significant increase in aggressive responding 6 h after the 25 g mixture compared to a baseline day when no drink was administered. There was also a significant decrease in plasma tryptophan at 5 hours after ingestion compared to baseline for both doses of amino acid mixture. This study supports the hypothesis that tryptophan depletion increases aggressive responding in healthy males in a laboratory setting; probably by decreasing brain serotonin.