ISSN:
1438-2199
Keywords:
Amino acids
;
Tissue protein synthesis
;
Stable isotope amino acids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The tracers L15N-proline and L(1-13C)-leucine were used to explore the synthesis of skin proteins in vivo in rabbits. They orally received a single dose containing an equimolecular mixture of L(1-13C)-leucine and L15N-proline. The changes in the amounts of these tracers in blood and skin were monitored for a total of 8 h. The data showed the appearance of the two tracers in blood within 15 min and their clearance in 8h. They were both rapidly (15 min) incorporated into skin proteins, but more proline was incorporated than leucine. We therefore consider L15N-proline to be a better tracer than L(1-13C)-leucine for studying protein metabolism in the skin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01321530
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