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  • 1
    Electronic Resource
    Electronic Resource
    Behavioural responses to stereotactically controlled injections of monoamine neurotransmitters into the accumbens and caudate-putamen nuclei (1980)
    Springer
    Psychopharmacology 71 (1980), S. 227-235 
    Details
    ISSN: 1432-2072
    Keywords: Exploratory behaviour ; Locomotor behaviour ; Stereotyped behaviour ; Dopamine ; Noradrenaline ; 5-Hydroxytryptamine ; Nialamide ; Intracerebral injection ; Nucleus accumbens ; Caudate-putamen ; Automated hole-board
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Bilateral stereotactically-controlled injections of dopamine (5–50 μg of the hydrochloride salt) into the nucleus accumbens of nialamide-pretreated rats induced a marked stimulation of exploratory and locomotor activity, accompanied by intense sniffing and rearing. Conversely, bilateral injection of dopamine (12.5–50 μg of the hydrochloride salt) into the caudate-putamen induced intense stereotyped activity which was dose-related. Both responses were blocked by IP haloperidol. Bilateral injection of noradrenaline (50 μg of the hydrochloride salt) into the accumbens nuclei did not produce any particular behavioural changes. The same injection into the caudate-putamen led to a moderate stimulation of stereotyped activity. Bilateral injection of 5-HT (50 μg of the bimaleinate salt) into the accumbens nuclei induced a moderate locomotor activity with some hole-dipping activity and sniffing; these behaviours were incoordinated and indecisive. The same injections into the caudateputamen led to a moderate stimulation of locomotor activity and hole-dipping which was predominantly “stereotyped” in character; on visual observation no other striking abnormalities were noted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433056
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    An automated method for studying exploratory and stereotyped behaviour in rats (1977)
    Springer
    Psychopharmacology 52 (1977), S. 271-277 
    Details
    ISSN: 1432-2072
    Keywords: Rat ; Exploratory behaviour ; Stereotyped behaviour ; Hole-board ; dl-Amphetamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A technique is described for studying exploratory as well as stereotyped behaviour in rats using an automated hole-board. Both visual and automated recordings can be employed using the technique. Hole dipping is monitored automatically using an infra-red detector system. Repetitive patterns of hole-dipping are used as parameters of stereotyped behaviour while the more random patterns of hole-dipping are used as parameters of exploration. There was a high significant correlation between the records of hole-dipping behaviour as recorded visually and automatically. There was also a high significant correlation between the measures of repetitiveness/randomness of hole-dipping behaviour from automatic and visual recordings. The pattern and levels of hole-dipping conformed with expectations both as regards changes with time and with increasing doses of dl-amphetamine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426711
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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