ISSN:
0170-2041
Keywords:
Cerium Compounds
;
1,7-Octadiynes, substituted
;
Allenes
;
Steroids
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The addition of (trimethylsilyl)propargylmagnesium bromide (9) to aldehydes afforded predominantly the allenylic alcohols rac-10. The regioselectivity of this addition changes dramatically when organocerium reagents were used for the addition. In this case nearly exclusive formation of the homopropargylic alcohols rac-8 was observed. Highest selectivity for this process was obtained when cerium(III) isopropoxide (13) was used as a precursor for the formation of the organocerium reagent.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199419940707
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