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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 165 (1975), S. 199-203 
    ISSN: 1433-8580
    Keywords: hypoxic stress ; stressulcer ; Vitamin A protective effect ; Hypoxie-Stress ; Stressulcus ; Vitamin A-Schutzeffekt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die protektive Wirkung von Vitamin A gegenüber stressinduzierten Ulcerationen der Magenschleimhaut wurde im Hypoxie-Stress der Ratte untersucht. Die Zahl der akuten Schleimhauterosionen im Hauptmagen der Tiere wurde durch vor oder zu Stressbeginn intramuskulär verabreichte Vitamin A-Gaben von 125 000 – 500 000 E/kg KG signifikant vermindert. Eine geringere Dosierung oder die Verabreichung 2 Stunden nach Stressbeginn beeinflußte die Entstehung von akuten Schleimhauterosionen nicht mehr.
    Notes: Summary The protective effect of Vitamin A against stress-induced ulcerations of the gastric mucosa was investigated by the hypoxic stress model of the rat. The incidence of acute mucosal erosions in the main stomach was significantly reduced by intramuscular application of 125 000 – 500 000 U Vitamin A/kg body weight prior to or immediately after the onset of stress. A dosage smaller than that or an application 2 hours after the onset of stress had no influence on the development of the acute mucosal erosions.
    Type of Medium: Electronic Resource
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