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  • 1
    Electronic Resource
    Electronic Resource
    Sequential enumeration of peripheral blood T cell subsets in lichen planus (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 9 (1984), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Peripheral blood T lymphocytes and T cell subsets were examined in fifteen patients with lichen planus prior to and for 4 months during treatment.The percentages of different T cell sub-populations were defined by indirect immunofluorescence using monoclonal antibodies OKT3, OKT4 and OKT8. These are specific markers of total T cells, helper-inducer T cells and suppressor-cytotoxic T cells respectively.Decreased percentages of suppressor T cells and elevated helper suppressor ratios were observed before treatment and after 1 month of therapy. These changes had disappeared by the second month of treatment, by which time all the lesions had healed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1984.tb00792.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of aromatic retinoid (Ro 109359) on Langerhans' cells in lichen planus (1983)
    Springer
    Archives of dermatological research 275 (1983), S. 105-108 
    Details
    ISSN: 1432-069X
    Keywords: Lichen planus ; Langerhans' cells ; Monoclonal antibodies ; Retinoid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Retinoids are used in the treatment of lichen planus (LP) disease, but their mechanism of action remains unknown. We studied the epidermal Langerhans' cells in four patients with chronic LP, before and after treatment with aromatic retinoids. This study uses a new technique of quantification and exploits two monoclonal antibodies — OKT 6 specific for Langerhans' cells and BL 2 specific for HLA-DR antigens. Our results show an increase in the number of dendritic epidermal cells after treatment with oral retinoids. The number of OKT 6-positive cells is greater than the number of BL 2-positive (HLA-DR) cells before and after treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00412884
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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