ISSN:
1573-8221
Keywords:
transplantation
;
lymphocytes
;
myocardium
;
dehydrogenases
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Succinate dehydrogenase (SD) and α-glycerophosphate dehydrogenase (α-GPD) activity were studied in the peripheral blood lymphocytes and grafted myocardium in CBA mice after transplantation of the heart from newborn C57BL/6 mice subcutaneously into the concha auriculae. The ratio SD/α-GPD was shown to be greater than 1 in the myocardium and lymphocytes of intact animals and in recipients of a transplanted isolinear heart. After allogeneic (heterolinear) transplantation the ratio between the activities was reversed (SD/α-GPD less than 1) on account of activation of α-GPD in the blood lymphocytes, and this was preceded by inversion in the myocardium of the graft. This phenomenon is assumed to be connected with the development of immunological conflict.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00797555
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