ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The characteristic mass spectral fragmentation patterns of the basic structure of the steroidal sapogenin, (25R)-5α-spirostan, have been elucidated through the preparation of analogs with deuterium labels at positions 11, 12, 14, 15, 16, 17, 20, 21, 23, 24, 25, 26 and 27. In addition, the effects of a change of stereochemistry at positions 14 and 20, of the introduction of oxygencontaining functionalities mostly in ring F, and of the incorporation of olefinic unsaturation have been determined through synthesis of many examples.
Additional Material:
14 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210030907
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