ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Asymmetric hydrosilylation of acetophenoxime and cyclic and acyclic imines (with subsequent hydrolysis to amines) was investigated using as catalyst a rhodium complex with the chiral phosphinamino ligand (S)-Phephos. With this method the chiral analog of the antidepressant Pyrazidol was synthesized with an optical yield of 73%.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00958569
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