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  • 1
    ISSN: 1432-2307
    Keywords: Interdigitating cells ; Histiocytoma ; Lymphoma ; Microscopy ; Electron ; Fluorescent antibody technic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A tumor in a 37 years old male is described in which the tumor cells appeared to be derived from interdigitating cells normally found in the T-cell area of lymph nodes. The patient presented with superior vena caval obstruction due to a mediastinal mass, followed by lymph node enlargement and skin lesions leading to death within 4 months. The tumor cells lacked immune markers for lymphocytic cells. They showed Ia-like antigens and high adenosine triphosphatase activity, while acid phosphatase and α-naphthyl acetate esterase activity was absent. Their fine morphology was strikingly similar to that of interdigitating cells. A combination of these data led us to the conclusion that this tumor represents a specific subtype of the tumors derived from the mononuclear phagocyte system, namely a sarcoma of interdigitating cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 124 (1972), S. 387-405 
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Mouse ; Follicular cells ; Marginal cells ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Follicular cells in the mouse adenohypophysis were studied electron microscopically. These elements appear to be very similar to the marginal cells that delineate both sides of the hypophyseal cleft. The mouse differs from most other species in that the follicular cells in the pars distalis and the marginal cells look completely inactive in young, intact animals. This makes the mouse exceptionally favorable for correlating morphological changes in the cells of both types with changes in the physiological state of the animal. Different treatments applied in the present investigation all induced morphological reactions in the follicular and/or marginal cells; these reactions were generally similar. Thus, morphological changes in the follicular or marginal cells should be considered as general phenomena accompanying many changes in the physiological state of the animal, rather than as a specific result of the treatment applied. In three experiments, the follicular and marginal cells were involved in the digestion of waste material from other cells. It is suggested that the morphological changes in the other experiments should also be interpreted as signs of such an activity. In the pars tuberalis of the young, intact mouse the follicular cells may show characteristics that in the pars distalis are found only under experimental conditions. Therefore, the follicular cells in this part of the hypophysis are probably in an active state.
    Type of Medium: Electronic Resource
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