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  • 1
    Electronic Resource
    Electronic Resource
    Salivary glands and noradrenergic transmission in diabetic rats (2002)
    Oxford, UK : Blackwell Science Ltd
    Autonomic & autacoid pharmacology 22 (2002), S. 0 
    Details
    ISSN: 1474-8673
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Chemistry and Pharmacology , Medicine
    Notes: 1 Type 2 diabetes is associated with diverse oral pathologies in which salivary flow reduction is one of the causes of these oral abnormalities. Scarce literature exists regarding noradrenergic transmission and adrenergic-induced salivary flow in submaxillary and parotid glands of type 2 diabetic rats. 2 We studied noradrenergic transmission as well as the secretory response to α1- and β-adrenoceptor stimulation in the parotid and submaxillary glands of type 2 diabetic rats. 3 Diabetic rats exhibited diminished neuronal uptake, release and endogenous content of noradrenaline (NE) in both salivary glands. Further, NE synthesis was also diminished accompanied by decreased tyrosine hydroxylase activity. Salivary flow responses to α1-(methoxamine) and β-(isoprenaline) adrenoceptor stimulation were reduced in the submaxillary as well as the parotid glands of diabetic rats. 4 Our results suggest that the reduction of noradrenergic transmission in the salivary glands of type 2 diabetic rats is in part responsible for the diminished salivary flow evoked by α1- and β-adrenergic stimulation. Reduced noradrenergic activity may contribute to the pathophysiology of oral abnormalities in diabetic patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1474-8673.2002.00243.x
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  • 2
    Electronic Resource
    Electronic Resource
    Interrelationship between the thyroid gland and sympathetic function (1973)
    Springer
    Cellular and molecular life sciences 29 (1973), S. 1291-1292 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen Se estudió en ratas Wistar macho, el efecto de la triiodotironina y el131I sobre el contenido y concentración noradrenalina y adrenalina, en glándula submaxilar y corazón. Se estudió también, el efecto del isoproterenol sobre el glucógeno de ambos órganos en animales controles e hipotiroideos experimentales. Se observó un comportamiento diferente en los depósitos de noradrenalina y adrenalina en los órganos estudiados. La triiodotironina produjo una disminución en la liberación o catabolismo de las catecolaminas y el131I parece causar el efecto opuesto y una disminución de la sensibilidad de los recptores adrenérgicos.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01935123
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of oophorectomy and sexual hormones on norepinephrine and epinephrine urinary excretion (1975)
    Springer
    Cellular and molecular life sciences 31 (1975), S. 1103-1104 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen Se estudió en ratas Wistar hembras, el efecto de la ovariectomía y la administración de estradiol, progesterona y testosterona, sobre la excreción urinaria de noradrenalina (NA), adrenalina (A) y al relación NA/A. La ovariectomía aumentó la excreción de A, disminuyendo la relación NA/A. El estradiol disminuyó la excreción de NA y la relación NA/A e incrementó la eliminación de A. La progesterona aumentó la excreción de NA, y la relación NA/A, la testosterona no modificó las catecolaminas urinarias.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02326984
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    Paper (German National Licenses)
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