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  • 1
    ISSN: 1434-0879
    Keywords: Allopurinol ; Blood pressure ; Renal stones ; Hyperuricaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The results of a prospective study of the development of hypertension and renal stone disease in subjects with increased blood urate are reported and compared with matched controls. None of the 14 patients on Allopurinol developed a renal stone but one untreated control did. For male patients there was a significant difference (p〈0.01) in diastolic blood pressure between the 2 groups over the 5-year study period, with treated patients having higher blood pressures than untreated controls. This suggests that Allopurinol has had no effect on lowering diastolic blood pressure. Long-term therapy with Allopurinol was effective in reducing mean blood urate levels. It is suggested that blood urate levels are more relevant in predicting renal stone formation and of less value in assessing the therapy and prognosis in hypertension.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 12 (1984), S. 213-215 
    ISSN: 1434-0879
    Keywords: Methyl-prednisolone ; Male sub-fertility ; Trace metals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of 96 mg methylprednisolone on trace metals and hormone levels was measured in 13 males with sub-fertility associated with an antibody problem. Over a period of 5 days the serum zinc was significantly reduced (p〈0.05) as was the serum testosterone (p〈0.01). By contrast the luteinising hormone levels rose (p〈0.01) within 3 days of administration of the steroid. The lability of serum zinc to the administration of steroids is further demonstrated by its significant fall (p〈0.01) after 3 days of therapy. These results suggest an adreno-cortical control of zinc in serum.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 12 (1984), S. 279-281 
    ISSN: 1434-0879
    Keywords: Antibiotic prophylaxis ; Transurethral resection of prostate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 65 men undergoing elective transurethral resection of the prostate under the care of one urologist entered a randomised controlled trial using Cefuroxime. Patients were excluded if they had received antibiotics in a 2 week period before surgery, if they had positive pre-operative urine cultures or if they had been catheterised. 58 patients completed the study. One patient in the antibiotic group and 2 in the control group developed urinary infection. The overall infection rate was 5.17%. The control and antibiotic groups were comparable as regards age and the duraction of resection. One patient in the antibiotic group developed an allergic reaction. It is felt that routine antibiotic prophylaxis in patients with sterile urine undergoing elective TUR is unnecessary.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 13 (1985), S. 77-78 
    ISSN: 1434-0879
    Keywords: Peak urine flow ; Urine infection and retention ; Cardiac surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Peak urine flow rates were measured in 83 men before coronary artery bypass grafting. The patients were grouped according to the method of Drach et al. [1] into those with normal, equivocal or abnormal flow rates. No cases of urine infection occurred in any of the 3 groups and only 2 patients in the group with abnormal peak flow developed urine retention. This was not statistically significant. Peak urine flow did not appear to be useful in predicting urine retention after coronary artery bypass grafting.
    Type of Medium: Electronic Resource
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