ISSN:
1432-0584
Keywords:
Interferon
;
Anemia
;
Hemolytic anemia Agglutinins
;
Autoimmune anemia
;
Immunoglobulin M autoagglutinins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We describe the beneficial effect of recombinant alpha 2b interferon in a woman with an idiopathic and refractory IgM-mediated autoimmune hemolytic anemia due to low-titer, high-thermal-amplitude cold agglutinins. The response was partial but sustained, 2 months after interruption of interferon, with hemoglobin concentrations ranging between 8.5 and 10 g/dl. In the literature, such rarely encountered hemolyzing warm-reacting agglutinins are described as causing severe hemolysis with a frequently fatal clinical outcome.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01695696
Permalink