ISSN:
1432-2013
Keywords:
Hypoxia
;
Carotid body
;
Pulmonary stretch receptors
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The early ventilatory response to transient hypoxia was examined in the anaesthetized rabbit. In intact spontaneously breathing animals, an increase in tidal volume (V T) with an accompanying slight increase in inspiratory duration (T I) and a decrease in the expiratory duration (T E) was observed. After vagotomy, the ventilatory response was distinguished by a greater increase inV T and a significant decrease inT I andT E. In another group of artificially ventilated rabbits, an increase in inspiratory volume with a simultaneous decrease in breathing frequency was found to involve a smaller reflex increase in phrenic inspiratory discharge after onset of transient hypoxia. These observations suggest that afferents from pulmonary vagal stretch receptors inhibit those from arterial chemoreceptors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00622905
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