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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 90 (1995), S. 377-386 
    ISSN: 1573-2622
    Keywords: Age-related macular degeneration ; Colour contrast sensitivity ; Soft drusen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The present institutional study was undertaken in order to determine whether testing of colour contrast sensitivity is valuable in detecting early functional changes in patients at initial stages of age-related maculopathy (ARM). The study included 27 patients with soft drusen as an early sign of ARM and 29 age-matched normals. The area occupied by drusen was determined using a computer program. Colour contrast sensitivity was measured with a computer graphics system. Visual acuity, central visual field (Humphrey Field Analyser) and colour vision (D-15 panel) were normal in both groups. Mean colour contrast sensitivity was significantly lower in patients with early ARM (for the protan axis: p=0.00019, for the deutan axis: p=0.000078 and for the tritan axis: p=0.000096) than in the controls. Interindividual variations were large. There was a tendency towards a bimodal distribution for all three colour axes, most evident for the tritan axis. We found a correlation of the drusen area with the protan and deutan thresholds for the fundus colour photographs r=0.5 (p〈0.01) and r=0.4 (p〈0.05), respectively, and with the tritan threshold for the angiograms r=0.5 (p〈0.05). The findings suggest that colour contrast sensitivity may offer an additional possibility of predicting exudative ARM. Whether the patients with the highest thresholds are those who will be the first to show progression with indications of exudative ARM is not yet known. The patient group will be followed up in order to elucidate this question.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2622
    Keywords: Age-related macular degeneration ; Eccentric viewing ; Low vision training
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A new approach designed to establish the most suitable area for eccentric viewing and to teach and train patients with severe age-related macular degeneration (AMD) to use the eccentric viewing technique is described. Using a computer and video display based system, as well as software written specifically for this purpose, we investigated and trained ten consecutive patients with AMD. The patients were 80.1 ± 5.6 years old, on average. All of them had an absolute central scotoma. Mean visual acuity was 0.035 ± 0.016. After 30 min of testing, instruction and reading on the screen, followed by 2.6 ± 0.69 one-hour training sessions, on average, with the low vision therapist, reading newspaper and book texts with the aid of hyperoculars or aplanatic systems and a very short reading distance, the patients achieved a reading speed of 58.9 ± 19.7 words/min, significantly (p〈0.001) higher than the initial speed when reading on the screen, 11.5 ± 4.5 words/min.
    Type of Medium: Electronic Resource
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