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  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 67 (1995), S. 1963-1965 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A multiwavelength laser system designed for precise and efficient tissue ablation under water was realized by simultaneously coupling radiation of a holmium:YAG laser, emitting at a wavelength of 2.12 μm and an erbium: YSGG laser at 2.79 μm into the same zirconium fluoride (ZrF4) fiber. The beam paths of the two lasers were collinearly combined taking advantage of the dispersion of an Infrasil prism. Fast video flash photographs and laser induced pressure transients simultaneously recorded with a PVDF pressure transducer were used to study the dynamics of bubble formation at the submerged fiber tip. The bubble size and the bubble lifetime were determined as a function of the wavelength and the delay time between the two different laser pulses. The results indicate that the combination of 2 and 3 μm radiation takes specific advantage of both wavelengths and strongly enhances the ablation efficiency of tissue under water. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 81 (2002), S. 571-573 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Optoacoustics, which combines the merits and most compelling features of light and sound, is a technique for diagnosing optical tissue properties and for performing noninvasive medical imaging. We present a detection method based on Schlieren optical imaging used to record optoacoustic waves generated with 6 ns long laser pulses. These waves result from irradiation of optically absorbing targets hidden deep inside highly scattering media. Since they are generated from one single shot, Schlieren images contain all the information necessary for the reconstruction of the absorbing structures. The detection method allows on-line imaging with a spatial resolution of about 30 μm with high contrast. The proposed real-time imaging system not only enhances the level of visible detail but it is ideally suited for monitoring dynamic tissue changes. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 66 (1989), S. 4496-4503 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Laser cutting of biological matter is explained by a combined action of evaporation and ejection of liquid. It is shown that when the depth of the incision is larger than its diameter and when a certain critical value of the intensity is exceeded, a new effect, a turbulent flow of the liquid layer, emerges as a result of the increased vapor pressure gradient. This turbulent flow is accompanied by the appearance of a number of additional effects. These are the occurrence of a local minimum in the dependence of the normalized recoil momentum as a function of the position of the beam focus, the formation of bumps and, connected with this, a change in the extent and velocity of the ejection. These effects are experimentally studied in the present investigation. In addition, it is shown that for cutting soft tissue the accuracy of focusing has a crucial influence on the depth of the generated incision and the extension of the created thermal damage zone.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Submarine landslides can generate sediment-laden flows whose scale is impressive. Individual flow deposits have been mapped that extend for 1,500 km offshore from northwest Africa. These are the longest run-out sediment density flow deposits yet documented on Earth. This contribution ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0649
    Keywords: 61.80.Ba ; 87.45.Bp ; 87.69.Gp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The damage created instantaneously in dorsal skin and in the subjacent skeletal muscle layer after CO2 and Er3+ laser incisions is histologically and ultrastructurally investigated. Light microscopical examinations show an up to three times larger damage zone in the subcutaneous layer of skeletal muscle than in the connective tissue above. The extent of thermally altered muscle tissue is classified by different zones and characterized by comparison to long time heating injuries. The unexpectedly large damage is a result of the change of elastic properties occurring abruptly at the transition between different materials. This leads to a discontinuity of the cutting dynamics that reduces the ejection of tissue material. We show that the degree of thermal damage originates from the amount of hot material that is not ejected out of the crater acting as a secondary heat source.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0649
    Keywords: 61.80.Ba ; 79.20.Ds ; 87.50.Eg ; 87.55.Hb ; 87.80.+s
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Bone ablation using different pulse parameters and four emission lines of 9.3, 9.6, 10.3, and 10.6 μm of the CO2 laser exhibits effects which are caused by the thermal properties and the absorption spectrum of bone material. The ablation mechanism was investigated with light- and electron-microscopy at short laser-pulse durations of 0.9 and 1.8 μs and a long pulse of 250 μs. It is shown that different processes are responsible for the ablation mechanism either using the short or the long pulse durations. In the case of short pulse durations it is shown that, although the mineral components are the main absorber for CO2 radiation, water is the driving force for the ablation process. The destruction of material is based on explosive evaporation of water with an ablation energy of 1.3 kJ/cm3. Histological examination revealed a minimal zone of 10–15 μm of thermally altered material at the bottom of the laser drilled hole. Within the investigated spectral range we found that the ablation threshold at 9.3 and 9.6 μm is lower than at 10.3 and 10.6 μm. In comparison the ablation with a long pulse duration is determined by two processes. On the one side, the heat lost by heat conduction leads to carbonization of a surface layer, and the absorption of the CO2 radiation in this carbonized layer is the driving force of the ablation process. On the other side, it is shown that up to 60% of the pulse energy is absorbed in the ablation plume. Therefore, a long pulse duration results in an eight-times higher specific ablation energy of 10 kJ/cm3.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 47 (1988), S. 259-265 
    ISSN: 1432-0649
    Keywords: 87.60.Gp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Laser cutting of gelatin and tissue with Er and CO2 lasers is explained by combined action of evaporation, ejection of liquid and elastic deformation of the region of radiation impact. It is shown that the ejection mechanism is more pronounced at 2.94 μm than at 10.6 μm. The use of high speed photography has revealed the influence of the temporal pulse shape. The experimental results are explained by a thermo-mechanical model.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 49 (1989), S. 527-533 
    ISSN: 1432-0649
    Keywords: 07.20.—n ; 42.30.—d ; 87.60.Gp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A technique is experimentally demonstrated, allowing one, with a time resolution of a few ns, to remotely measure the temperature distribution on surfaces that are accessible to light. The surfaces are coated with a polymer containing fluorescing dye. When excited at the desired moment with a flashlight this is induced to fluoresce. As the fluorescence yield is temperature dependent, the temperature distribution during the fluorescence decay time can be uniquely determined. The fluorescence is recorded first in thermal equilibrium and then at the elevated temperature for which knowledge of the temperature distribution is desired. From the ratio of the spatially resolved fluorescence yields the temperature distribution can be evaluated. With spatial resolutions down to 2 μm, temperatures in the range 20°–120°C are measured with accuracies of ±1°C, where the measurement intervals are as short as 18 ns.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 58 (1994), S. 309-315 
    ISSN: 1432-0649
    Keywords: 42.81.-i ; 42.60.Jf ; 87.80.fs ; 79.20.Ds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A sapphire micro-lens system in combination with a zirconium-fluoride (ZrF4) fibre has been designed and constructed as a surgical tool for focusing Er:YAG-laser radiation. It both refocuses the laser radiation transmitted through a 350 µm core fibre to a spot diameter of 570 µm at a working distance of 7.6 mm, and protects the distal fibre end from damage. An accurate and uncomplicated visualization of the focus position of the erbium-laser beam is realized by coupling a HeNe aiming laser into the cladding of the fibre. In vitro cutting experiments reveal the high cutting precision with minimal thermal damage of the surrounding tissue and the high damage resistance of the system. It may render the use of the erbium laser possible in a wide range of endoscopic applications.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0649
    Keywords: PACS: 42.62.Be; 62.50.+p; 87.45.-k
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: 5  Pa served as tissue phantoms to evaluate such effects. Holmium laser pulses (wavelength: 2.12 μm, duration: 180 μs FWHM), were delivered through 400 and 600 μm diameter optical fibers inserted into cubes of clear gel. Bubble effects were investigated using simultaneous flash micro-videography and pressure recording for radiant exposures of 20–382 J/cm2. Bubble formation and bubble collapse induced pressure transients were observed regardless of phantom stiffness. Bubbles of up to 4.2 mm in length were observed in gels with a Young’s modulus of 2.9×105 Pa at a pulse energy of 650 mJ. An increase of Young’s modulus (reduction in water content) led to a monotonic reduction of bubble size. In the softest gels, bubble dimensions exceeded those observed in water. Pressure amplitudes at 3 mm decreased from 100±14 bars to 17±6 bars with increasing Young’s modulus over the studied range. Theoretical analysis suggested a major influence on bubble dynamics of the mass and energy transfer through the bubble boundary.
    Type of Medium: Electronic Resource
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