ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The polarographic behavior in dimethylformamide of the o-, p-, and m-isomers of 5-(nitrophenyl)-2-furfural and their benzoylhydrazones has been studied. These compounds give one one-electron and one three-electron wave of the reduction of the nitro group, the corresponding half-wave potentials being considerably more negative than the half-wave potentials of 5-nitro-2-furfural and the corresponding nitrobenzaldehydes. In the case of 5-(o-nitrophenyl)-2-furfural and its benzoylhydrazone, a hydrogen bond is formed between the nitro group and the furan ring or the amide grouping of the side chain, which leads to a considerable shift in the potentials in the negative direction. Because of the high electroreduction potentials, the benzoylhydrazones of the 5-(o-, p-, and m-nitrophenyl)-2-furfurals have no antibacterial and fungistatic activity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00470247
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