Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Acquired haemophilia: experiences with a standardized approach (2001)
    Oxford UK : Blackwell Science Ltd
    Haemophilia 7 (2001), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Acquired haemophilia is a rare, life-threatening, acquired bleeding diathesis. No general consensus exists on the best therapeutic approach. We report on the standardized approach at our institution evaluated in ten patients with acquired haemophilia. Factor VIII inhibitors were found in all patients, activities ranging from 1 to 648 Bethesda units (BU). Eight of the ten patients presented with severe bleeding. Two patients died during the acute phase, one from intracranial bleeding and one due to Mycoplasma pneumonia. One patient with mild bleeding was treated with immunosuppression alone. Two patients with factor VIII inhibitor activities below 5 BU were started on factor VIII concentrate therapy. Therapy was successful in one and was changed to recombinant human activated factor VII infusion (rFVIIa) in the other, owing to insufficient factor VIII recovery. Six patients with factor VIII inhibitor activities above 5 BU were started on activated prothrombin complex concentrate (APCC) therapy. APCC treatment was successful initially in all six patients and was changed to rFVIIa infusion in one for rebleeding. One patient did not receive any specific therapy. Immunosuppression with prednisolone (2 mg kg−1) was begun in nine patients and was continued with cyclophosphamide (2 mg kg−1) in six. A complete remission of the acquired haemophilia was found in seven of the eight patients surviving the acute phase, one had a partial remission. All patients with acquired haemophilia could be managed effectively following our standardized approach. Routine administration of immunosuppression was associated with high inhibitor elimination rates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2516.2001.00488.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    56jähriger Patient mit segmental florider Colitis und Colonamyloidose (1999)
    Springer
    Der Internist 40 (1999), S. 668-672 
    Details
    ISSN: 1432-1289
    Keywords: Schlüsselwörter Colonamyloidose ; Chronisch-entzündliche Darmerkrankung ; Ischämische Colitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Bei einem 56jährigen Patienten wird 1/97 die Erstdiagnose einer chronisch-entzündlichen Darmerkrankung des Kolons gestellt, die am ehesten einem Morbus Crohn entspricht. Sechs Monate später wird histologisch eine massive Colonamyloidose beschrieben, die retrospektiv bereits bei der Erstmanifestation der Erkrankung vorlag. Weitere Organbeteiligungen können nicht nachgewiesen werden können. Die immunhistochemischen Untersuchungen schließen eine AA-Amyloidose aus. Vermutlich liegt eine Leichtkettenamyloidose vor. Unter Therapie mit 5-ASA befindet sich der Patient seit über einem Jahr in klinischer Remission. Die Amyloidablagerungen persistieren, dagegen findet sich weiterhin kein Anhalt für eine Beteiligung anderer Organsysteme.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001080050387
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Gastric Hypersensitivity in Nonulcer Dyspepsia An Inconsistent Finding (1997)
    Springer
    Digestive diseases and sciences 42 (1997), S. 720-723 
    Details
    ISSN: 1573-2568
    Keywords: BAROSTAT ; NONULCER DYSPEPSIA ; VISCERAL HYPERSENSITIVITY ; H. PYLORI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Visceral hypersensitivity is claimed to beinvolved in the pathogenesis of nonulcer dyspepsia(NUD). We evaluated whether gastric hypersensitivity isa consistent finding in an unselected group of NUDpatients. In 11 patients and 20 healthy controls, astandardized gastric distension was performed using agastric barostat. Perception was scored by aquestionnaire and compared between the two groups. Therewas a linear pressure/volume relationship duringgastric distension in both groups. The pain threshold inNUD patients was significantly lower compared tocontrols [5.5 ± 4.0 mm Hg above minimaldistending pressure (mdp) and 10.2 ± 2.2 mm Hg above mdp,respectively, P 〈 0.004], irrespective of the H.pylori status. However, more than 50% of the NUDperception scores were in the control range at mostdistension levels. Gastric hypersensitivity could be confirmed inNUD patients as a group. However, there is aconsiderable overlap concerning perception in responseto distension between unselected NUD patients andcontrols.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018891409189
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...