ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis and Reactions of the Bicyclo[6.4.0]dodecane-3-carboxylic Acid DerivativesThe synthesis and some consecutive reactions of the compounds 5-8, derivatives of bicyclo[6.4.0]dodecane-3-carboxylic acid (1), are described. The esters 7 and 8 can be obtained by Baeyer-Villiger oxidation of 2-hydroxy-8-methyltricyclo[7.3.1.02,7]tridecan-13-one (4) and subsequent hydrolysis of the lactone 5. The structure and configuration of these compounds has been evaluated by spectroscopic techniques (mainly 2D-NMR methods). The formation of 7 via 1,2-H shift and subsequent isomerization to 8 has been studied. The esters 11 and 13 are formed stereospecifically from 7 and 8.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19850680129
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