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  • 1
    Electronic Resource
    Electronic Resource
    Radioimmunoassay and chemical properties of glucose-6-phosphate dehydrogenase and of a specific NADP(H)-binding protein (FX) from human erythrocytes
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/General Subjects 500 (1977), S. 109-123 
    Details
    ISSN: 0304-4165
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0304-4165(77)90051-4
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of platelet membranes on the electrophoretic pattern of 6-phosphogluconic dehydrogenase from platelet lysates (1972)
    Springer
    Cellular and molecular life sciences 28 (1972), S. 572-574 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto L'incubazione di lisati piastrinici con NADP provoca inattivazione della 6PGD e ne modifica la migrazione elettroforetica. Non si osserva invece attivazione della GSSG-R.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01931885
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  • 3
    Electronic Resource
    Electronic Resource
    Absence of haemolytic effects of L-DOPA on transfused G6PD-deficient erythrocytes (1970)
    Springer
    Cellular and molecular life sciences 26 (1970), S. 785-786 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto Eritrociti G6PD deficienti, marcati con Cr 51, sono stati trasfusi in soggetti normali cui venivano somministrate giornalmente dosi di L-DOPA per via venosa. La L-DOPA viene usata per la terapia del morbo di Parkinson, e causa in vitro una perdita di GSH dagli eritrociti G6PD deficienti. Non si sono osservate modificazioni nella curve della radioattività ematica come conseguenza della somministrazione della L-DOPA. Si conclude pertanto che tale farmaco non ha effetti emolizzanti sugli eritrociti con carenza enzimatica di G6PD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02232551
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  • 4
    Electronic Resource
    Electronic Resource
    Unusual bone marrow relapse of Hodgkin's disease with typical Pel-Ebstein fever (1996)
    Springer
    Annals of hematology 73 (1996), S. 39-40 
    Details
    ISSN: 1432-0584
    Keywords: Key words Hodgkin's disease ; Relapse ; Bone marrow ; Fever
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We report the unusual case of a 43-year-old man with a diagnosis of clinical stage I A mixed cellularity Hodgkin's disease (HD), who relapsed 4 years after diagnosis with exclusive bone marrow involvement and a cyclic variation in body temperature typical of Pel-Ebstein fever. In the absence of clinical and laboratory signs of infection, a restaging of the lymphoma was performed. Total-body CT scan revealed no parenchymal or lymph node involvement, while a bone-marrow biopsy was positive for the presence of Reed-Sternberg cells. Therefore, the patient was started on combination chemotherapy, which promptly induced a normalization of the temperature curve. The presence of typical Pel-Ebstein fever, which is reported to be very rare, in association with bone marrow localization as the only site of relapse, suggests a relationship between these two rare manifestations of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050198
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  • 5
    Electronic Resource
    Electronic Resource
    Familial Hodgkin's disease: a disease of young adulthood? (1997)
    Springer
    Annals of hematology 74 (1997), S. 131-134 
    Details
    ISSN: 1432-0584
    Keywords: Key words Hodgkin's disease ; Sex ; Age ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Familial Hodgkin's disease (FHD) is estimated to represent approximately 4.5% of all cases of Hodgkin's disease (HD). Shared environmental factors, such as Epstein-Barr virus and other viral agents, and genetic determinants have all been proposed to explain familial aggregation of HD. In order to compare the characteristic features of FHD with those of the much more common sporadic form, we reviewed 28 articles on FHD, published between 1972 and 1995, and analyzed in further detail data from 18 papers, reporting on a total of 328 patients. The male-to-female ratio of the FHD population examined was 1.5, similar to that reported for sporadic HD, and lower than the one suggested for FHD by some authors. On the other hand, a significant difference was found between sporadic and familial HD according to age at diagnosis; that is, only one major peak between 15 and 34 years was present in the group of patients with FHD. Further investigation of FHD in young adulthood may provide insight into the hypothesis of a genetic or infectious etiology of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050270
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  • 6
    Electronic Resource
    Electronic Resource
    Ein Beitrag zur Frage der Geschwulsttransplantation mit ausgezähltem Zellmaterial (1936)
    Springer
    Journal of cancer research and clinical oncology 44 (1936), S. 108-129 
    Details
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung In einer Suspension mit 1 ccm physiologischer Kochsalzlösung war die niedrigste Anzahl von Geschwulstzellen, bei der Angehen und Wachstum eines Transplantates des Adenocarcinoms Ehrlich 5 beobachtet wurde, in der Größenordnung von 430 000. Enthielt die Suspension reichlich Detritus von nekrotischem Tumormaterial, so kam es noch bei 300 000 Zellen zum Angehen und gutem Wachstum des Geschwulstmaterials. In konzentrierter Form, als Bodensatz des Zentrifugats einer Suspension, genügten häufig 100 000 Zellen zum Angehen und manchmalzureichlichem Wachstum der Geschwulst. Unterhalb dieses Wertesging auch als konzentrierter Bodensatz ein Transplantatniemals an. Zusatz von Organbrei homologer normaler Tiere war nicht von erheblicher Bedeutung für Angehen und Wachstum der Geschwulst-transplantate, ebensowenig ein solcher von heterologen Organen (Meerschweinchen). Dagegen bewirkte ein Zusatz von Organen einer geschwulstkranken Maus eine deutliche Vermehrung der Angangszahl. Doch gingen die Geschwülste sämtlich wieder zurück. Ein eindeutiger Unterschied in der Wirksamkeit des Zusatzes der untersuchten Organe (Gehirn, Leber, Lunge, Milz, Niere) ließ sich im allgemeinen nicht feststellen. Eine bemerkenswerte Ausnahme machte der Zusatz von Nierenbrei, der das Angehen des Geschwulsttransplantates begünstigte. Zusatz von Brei eines Adenocarcinoms der menschlichen Mamma zum Geschwulsttransplantat von 100 000 Zellen des Mäusetumors und in noch stärkerem Ausmaße Zusatz von 1 ccm eines Berkefeld-Filtrates vom Rous-Sarkom des Huhnes begünstigten Angehen und Wachstum der Transplantate in ausgesprochener Weise. Diese Wirkung des Berkefeld-Filtrats von Rous-Sarkom ging verloren, wenn man den Geschwulstbrei 24 Stunden auf Eis in Kontakt mit dem Berkefeldfiltrat beließ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01668047
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