ISSN:
0170-2041
Keywords:
3-Deoxyprumycin
;
Amino acids
;
Peptides
;
Antifungal agents
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A number of 3-deoxy-DL-prumycin analogues containing one or more amino acid moieties were synthesized. Key intermediate 2 afforded ester analogues by coupling with H-D- or L-Ala-OH, while intermediates 6 and 9 afforded amide analogues by coupling with H-D-Ala-D-Ala-OH, H-D-Ala-OH, 2-amino-4,4-dichlorobutanoic acid and acetic acid. The antifungal activity of the analogues against various phytopathogenic fungi was measured.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199419940814
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