ISSN:
1432-1084
Keywords:
Bone mineral density
;
Quantitative computed tomography
;
Aging
;
Gender
;
Normative database
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The purpose of this study was to describe the normal cross-sectional pattern of spinal bone loss associated with aging in an Italian population and to compare these values to the American normative database. A group of 472 healthy subjects (382 females and 90 males) were recruited for bone mineral density (BMD) assessment by quantitative computed tomography (QCT). To eliminate technique-related differences in a comparison of Italian and American normal values obtained with two different scanners we performed a cross-calibration analysis scanning the same computerized imaging reference system (CIRS) phantom at both centers. The results of the cross-calibration study using the CIRS phantom were used to compare regression slopes of BMD with age and age-adjusted mean BMD of American men and women vs cross-calibrated Italian men and women. American men and women decrease more rapidly vs Italian men and women, and Italian men have significantly lower age-adjusted mean BMD than American men. For these reasons we recommend normal values to be locally obtained for an Italian population.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00185311
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