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  • 1
    ISSN: 1360-0443
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Prospective data from the California Tobacco Surveys (n=2066) were used to perform a critical test of the Prochaska et al. (1991) stages of change model. When the stages of change model was used as a stand alone predictor, smokers in preparation at baseline were more likely to be in cessation at follow-up than smokers in pre-contemplation at baseline (OR adj="1.9)" When stage membership was combined with baseline measures of addiction including smoking behaviors and quitting history, it was not a significant predictor of future cessation. A prediction equation that combined daily vs. occasional smoking, cigarettes per day smoked, life-time quits of at least a year, and quits of more than 5 days in the previous year discriminated smokers in cessation at follow-up of 1 to 2 years better than did the stages of change model. The area under the ROC curve for the equation based on addiction measures was 69.3% vs. 55.1% for the stages of change. Cessation rates ranged from 7.7% to 35.7% for the four-category addiction equation compared with 15.1% to 24.9% for stages of change model.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Carfax Publishing Limited
    Addiction 93 (1998), S. 0 
    ISSN: 1360-0443
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Objective. To extend the quitting continuum to categorize smokers in the early stages of the process of smoking cessation. Design. A prospective computer assisted telephone interview study with initial interviews in 1990 and reinterviews in 1992. Setting and participants. In California, 2514 current smokers and quitters of less than 5 years duration, selected randomly from a large scale cross-sectional survey in 1990. Results. We focus on smokers with high addiction (15 cigarettes/day) and without a strong quitting history (1 week in last year or 1 year ever) at baseline (N=822). Having an intention to quit and a limited quitting history (1-6 days in last year) was predictive of progress at follow-up into higher continuum levels ultimately associated with successful cessation. Furthermore, smokers with one trait were much more likely to progress than those with none. Accordingly, the lowest level of the earlier continuum was further subdivided into three subgroups (making eight levels overall). Over approximately a 2-year period, most smokers either progressed or regressed only one or two levels along the quitting continuum. Conclusions. Better than expected progress along this expanded quitting continuum could be a criterion for a successful intervention. Tailored interventions that move smokers to a higher level on the continuum should be a priority for future research.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Carfax Publishing, part of the Taylor & Francis Group
    Addiction 96 (2001), S. 0 
    ISSN: 1360-0443
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Aims. To determine whether the probability of future current established smoking among adolescents is related to both previous smoking experience and cognitions regarding future smoking. Design, setting and participants. The analyses used two principal datasets: (1) a US longitudinal sample of 7960 adolescents 12-18 years old in 1989 reinterviewed at 15-22 years in 1993, (2) a California longitudinal sample of 3376 adolescents 12-17 years old in 1993 reinterviewed at 15-20 years in 1996. Measures. Previous smoking experience was categorized as never smoked, puffed, non-recent or recent experimenting, and non-recent or current established smoking (≥ 100 cigarettes in life-time). Smoking intentions and efficacy expectations were used to classify adolescents as having low- or high-risk cognitions. Findings. High-risk cognitions (HRCs) increased the probability of future current established smoking (FCES) within each level of previous smoking experience over low-risk cognitions (LRCs); the probability of FCES for those with LRCs was about the same as those in the previous experience group with HRCs. In the US sample, the 4-year probability of FCES ranged from 5.6% for committed never smokers (with LRCs) to 83.0% for current established smokers with HRCs. Development of HRCs among middle-school never smokers occurred rapidly through age 14 years. However, current established smoking did not increase until age 14 years and stabilized by age 19 years. Where sample size was sufficient, these findings were validated in the California sample. Conclusions. Effective prevention programs should aim to convert HRCs to LRCs regardless of past behavior, particularly among middle-school never smokers and high-school experimenters.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Addiction 100 (2005), S. 0 
    ISSN: 1360-0443
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Aim  To compare predictors of smoking initiation in two longitudinal studies in California conducted during periods when adolescent smoking prevalence was increasing (1993–96) and decreasing (1996–99).Design, setting and participants  Cohorts of 12–15-year-old never smokers were identified from the cross-sectional 1993 and 1996 California Tobacco Surveys (large population-based telephone surveys) and followed-up 3 years later (1993–96, n = 1764; 1996–99, n = 2119).Measures  We compared cohort transition rates to any smoking by follow-up in risk groups defined by known predictors of smoking initiation at baseline. Besides examining predictors individually, risk groups were defined using a multivariate analysis.Findings  Overall, transition to any smoking by follow-up occurred in 38.3 ± 4.0% (% ± 95% confidence interval) of never smokers in the 1993–96 cohort and 31.1 ± 2.6% in the 1996–99 cohort. For most predictors, the transition rate for adolescents with the characteristic was the same or only slightly lower in the 1996–99 cohort compared to the 1993–96 cohort, but the transition rate in those without the characteristic was generally much lower, thus increasing the power of the predictor. The multivariate analysis confirmed that compared to the 1993–96 cohort, transition occurred much less often in the 1996–99 cohort for adolescents at low rather than at medium or high risk of future smoking.Conclusions  The turnaround in California adolescent smoking in the mid-1990s, when smoking began to decline, appears to come primarily from adolescents already at low risk of future smoking (as defined by a variety of predictors), who transitioned to smoking at much lower rates than previously.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 263 (1976), S. 497-499 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the textbook model of an overdominant polymorphism, two alleles, A and B, segregate at a locus, the frequency of allele A indicated by ( ) and the genotypes AA, AB and BB have relative fitnesses 1? s1 1 and 1?s2, respectively, where 0 〈 s 〈 1. It is easily shown that the equilibrium ...
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1971
    Keywords: Radiation exposure ; Renal anomalies ; Postcatheter urogram
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Postangiography urography has become routine procedure in most centers performing cardiac catheterization in children. We analyzed the x-radiation dosage and clinical yield of this procedure. Using lithium fluoride thermoluminescent dosimeters, radiation exposure to the abdomen and gonads was measured in 35 children during postangiography urography. Results of 334 consecutive routine postangiography cine-urograms were evaluated based on clinical significance and compared to previous reports on this subject. Averageabsorbed abdominal radiation dosage was 241 mR ±240 from cine-urography, 16 mR ±13 from fluoroscopy, and 107 mR ±111 from a single abdominal roentgenogram. Gonadal dosage averaged 8 mR and was uniformly less than 27 mR. Of 334 routine postangiography cineurograms, 282 (84%) were normal, 30 (9%) were technically inadequate, 12 (3%) had abnormalities that were clinically insignificant or were falsely “positive” and in 10 (3%), clinically significant urologic conditions were confirmed. Because of the low yield of clinically significant anomalies and the added radiation exposure, we no longer perform routine postangiography cine-urography in children. Following cardiac angiography, the upper renal collecting systems are examined fluoroscopically. If abnormalities are suspected or fluoroscopy is equivocal, a single abdominal roentgenogram is performed. Using this procedure, mean average absorbed abdominal radiation dose can be reduced from 241 mR to 30.5 mR.
    Type of Medium: Electronic Resource
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