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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 233 (1971), S. 26-36 
    ISSN: 0005-2736
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron Letters 7 (1966), S. 49-53 
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Diabetologia 28 (1985), S. 452-457 
    ISSN: 1432-0428
    Keywords: Alloxan-induced diabetes ; myocardium ; hyperglycaemia ; calcium ; magnesium ; ATPase activity ; lysosomal enzymes ; diabetic cardiomyopathy ; rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Biochemical and myocardial functional changes were determined in rabbits made diabetic with alloxan (100mg/kg, intravenously, two injections 24 h apart). Alloxan-induced diabetes was characterized by a state of hypoinsulinaemia and hyperglycaemia. After 10 weeks of diabetes, significant decreases in heart and left ventricular weights as well as increased serum and heart triglycerides and cholesterol were observed in the diabetic animals (p 〈 0.05). In addition, left ventricular pressure, heart rate and rate of left ventricular pressure development were all decreased in the animals. The diabetic state was also associated with a slight elevation in myocardial calcium and a significant decrease in magnesium levels (p 〈 0.05). Subcellular fractionation of diabetic hearts indicated the presence of alterations in myofibrillar and sarcoplasmic reticulum marker enzymes (p 〈 0.05). Among the lysosomal enzymes, measured, N-acetyl-β-glucosaminidase activity was significantly increased in the homogenates of diabetic left ventricles (p 〈 0.05). These alterations in hearts of diabetic rabbits may be responsible for some aspects of diabetic cardiomyopathy.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 29 (1991), S. 585-590 
    ISSN: 1741-0444
    Keywords: Amplifier noise ; Disk electrodes ; Electrodes ; Impedance ; Myoelectric signals ; Neuroelectric signals ; Noise ; Skin surface ; Stainless steel ; Thermal noise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Bioelectric events measured with surface electrodes are subject to noise components which may be significant in comparison with low-level biological signals such as evoked neuroelectric potentials, and myoelectric potentials. In an effort to better understand noise arising from these electrodes, electrode and measurement system noise is modelled. The effect of electrode surface area on electrode impedance and noise is studied using circular stainless-steel electrodes of varying diameters. The main contributions of the work are the development of a model for stainless-steel electrode noise as a function of electrode area, and demonstrating that, for the band-width of interest to evoked neuroelectric and myoelectric signals (8–10 000 Hz), the primary noise components are thermal and amplifier current generated. The magnitudes of both of these depend on the electrode impedance magnitude. Electrode impedance is shown to be a power function of both electrode diameter and frequency, consistent with a capacitive electrode model.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 11 (1979), S. 1-7 
    ISSN: 0091-7419
    Keywords: erythrocyte membranes ; LCAT deficiency ; electron spin resonance ; spin label ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The membrane fluidity of erythrocytes from patients with Lecithin: cholesterol acyltransferase (LCT) deficiency was studied by means of electron spin resonance. The temperature dependence of the separation of the outer extrema of the spectra of 2-(3-carboxy-propyl)-4,4-dimethyl, 2-tridecyl-3-oxazolidinyloxyl spin probe was monitored for normal, presumed carrier and clinically affected subjects. The temperature profile of controls was significantly different form that of the presumed carriers and the clinically affected individuals. The results show that the compositional abnormalities previously noted in erythrocyte membranes from patients with LCAT deficiency are associated with alterations in the physicochemical state of the membrane. An investigation of the spectral lineshapes below 10°C allowed a distinction to be made at the membarne level between clinically affected subjects and clinically normal heterozygous carriers. Alterations in the temperature dependence of electron spin resonance parameters may provide a sensitive index of red cell membrane alterations in pathological states of generalized membrane involvement.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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