ISSN:
1573-8221
Keywords:
aldosterone metabolism
;
experimental hypertension
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The mechanisms of the hypotensive effect of portocaval transposition were investigated in dogs with vasorenal hypertension. Directing blood flowing from the kidneys and adrenals into the liver in dogs with vasorenal hypertension was found to increase aldosterone metabolism and, at the same time, to increase aldosterone secretion by the adrenals, as a result of which the level of the steroid in the peripheral blood returned to normal. Abolition of the syndrome of secondary hyperaldosteronism by portocaval transposition of the vessels takes place on account of increased aldosterone metabolism and leads to restoration of the normal arterial pressure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00799186
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