ISSN:
0947-6539
Keywords:
combinatorial chemistry
;
compound libraries
;
drug research
;
solid-phase synthesis
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Through the advantages conferred in the speed of synthesis, combinatorial chemistry is making a significant impact on the process of drug discovery. The mix-and-split paradigm has been an effective method for the production of compound mixtures, although there is now a need for new, fast library approaches to generate well-characterised single compounds. Having already demonstrated the successful preparation and application of library mixtures, we have now developed a novel combinatorial method for the production of single compounds.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chem.19970031204
Permalink