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  • 1
    Electronic Resource
    Electronic Resource
    Intergalactic Matter (1968)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 6 (1968), S. 195-214 
    Details
    ISSN: 0066-4146
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.aa.06.090168.001211
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  • 2
    Electronic Resource
    Electronic Resource
    Goodness of trees for generalized books (1987)
    Springer
    Graphs and combinatorics 3 (1987), S. 1-6 
    Details
    ISSN: 1435-5914
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract A connected graphG is said to beF-good if the Ramsey numberr(F, G) is equal to(x(F) − 1)(p(G) − 1) + s(F), wheres(F) is the minimum number of vertices in some color class under all vertex colorings by χ (F) colors. It is of interest to know which graphsF have the property that all trees areF-good. It is shown that any large tree isK(1, 1,m 1,m 2,...,m t )-good.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01788524
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  • 3
    Electronic Resource
    Electronic Resource
    Immunocytochemical localization of platelets in baboon hepatic sinusoids using monoclonal mouse anti-human platelet glycoprotein IIIa following induction of thrombocytopenia (1992)
    Springer
    Histochemistry and cell biology 97 (1992), S. 355-360 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A commercially available mouse monoclonal antibody to human platelet glycoprotein IIIa was used to demonstrate sequestration of platelets in hepatic biopsies obtained from baboons following intravenous infusion of echistatin, a novel fibrinogen receptor antagonist derived from the venom of the snake Echis carinatus. Biopsies of liver and spleen were taken prior to administration of echistatin. The hepatic biopsies were either snap-frozen in Freon-22/liquid nitrogen or fixed in 10% neutral buffered formalin. Biopsies of spleen were snapfrozen. During infusion of echistatin (2.3 µg/kg/min), circulating platelet counts decreased from 331000/mm3 to 167000/mm3. Selective sequestration within the liver was confirmed using whole body gamma camera imaging to demonstrate 111Indium-oxine labeled platelet accumulation within the liver during the thrombocytopenic episode. Hepatic biopsies were again taken and either snap-frozen in Freon-22/liquid nitrogen or fixed in 10% neutral buffered formalin. Biopsies of spleen and inguinal lymph node were also snap-frozen. Platelet rich plasma smears, included as positive controls, dewaxed paraffin sections, and cryosections of liver, spleen, and lymph node were stained with monoclonal mouse anti-human platelet glycoprotein IIIa using an avidin biotinylated peroxidase complex (ABC) technique. Prior to infusion of echistatin, platelet staining within the liver was minimal. After echistatin infusion, hepatic cryosections showed prominent platelet staining within hepatic sinusoids. No localization was shown in lymph node, however, the spleen showed prominent platelet staining both before and after echistatin infusion. Platelet rich plasma smears were intensely positive. No prominent platelet staining was observed in formalin-fixed, paraffin-embedded material. Thus, this immunocytochemical technique may help localize platelets in cryosections of tissues from baboons and other primate species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00270038
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  • 4
    Electronic Resource
    Electronic Resource
    Laparoscopic-assisted colectomy (1995)
    Springer
    Surgical endoscopy and other interventional techniques 9 (1995), S. 1179-1183 
    Details
    ISSN: 1432-2218
    Keywords: Laparoscopic ; Colectomy ; Complications
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One hundred fifty consecutive laparoscopic-assisted colectomies performed by a surgical team were analyzed in an attempt to define a learning curve. These colectomies performed by the Norfolk Surgical Group over a 24-month period, were divided chronologically into six groups of 25 patients each. The groups were then compared to determine if any improvement in length of procedure, complication rate, conversion rate, or length of stay developed as experience increased. Colon cancer and diverticular disease were the most common indications for surgery in all groups. Right hemicolectomy, left colectomy, and low anterior resection accounted for the majority of procedures in all groups. A significant decrease in mean operative time, from 250 min to 156 min over the first 35–50 cases was observed before leveling off at approximately 140 min for the remaining groups. Intraoperative complications were low in all groups (range zero to two) and did not show any trend. There was no statistically significant difference in the conversion rate (23.3% overall) among the six groups. Length of stay decreased from 6 days in the first two groups to 5 days in the last four groups, although the difference was not statistically significant. The learning curve for laparoscopic-assisted colectomies is longer than appreciated by many surgeons, requiring as many as 35–50 procedures to decrease operative time to baseline. Complications can be kept at an acceptably low level while on the curve if a cautious approach is taken and the surgeon realizes that a prolonged operative time is not only acceptable, but appropriate during this long learning process. A conversion rate of 20–25% at any phase of the learning process may in fact represent a limitation of current technology. When combined with a low complication rate it may be the sign of a careful surgeon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210923
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  • 5
    Electronic Resource
    Electronic Resource
    Laparoscopic cholecystectomy in pregnancy (1996)
    Springer
    Surgical endoscopy and other interventional techniques 10 (1996), S. 314-318 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Laparoscopic — Cholecystectomy — Pregnancy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Although pregnancy was initially considered an absolute contraindication to laparoscopic cholecystectomy, there have been several case reports of successful laparoscopic cholecystectomy in pregnant patients in the literature over the past 4 years. We report our experience with six patients managed successfully with laparoscopic cholecystectomy during pregnancy. Methods: More than 1,300 laparoscopic cholecystectomies were performed by the Norfolk Surgical Group between May 1991 and June 1994. Six of these patients (∼0.5%) were operated on during pregnancy. We reviewed the management and operative technique used in these patients compared to our standard approach. The available literature was reviewed to identify any other factors which might be helpful in the management of these patients. Results: In this series we were able to perform laparoscopic cholecystectomy successfully in all six patients in whom it was attempted, with an overall course similar to that of nonpregnant patients. There were no significant complications to the patient or the fetus. All six patients have delivered healthy children and continue to do well. Discussion: With the addition of our 6 patients, there have been 32 successful laparoscopic cholecystectomies during pregnancy reported in the English literature. We feel laparoscopic cholecystectomy can be performed safely in pregnant patients and should be considered in any patient who presents with symptomatic cholelithiasis during pregnancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649910049
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  • 6
    Electronic Resource
    Electronic Resource
    Laparoscopic cholecystectomy in pregnancy (1996)
    Springer
    Surgical endoscopy and other interventional techniques 10 (1996), S. 314-318 
    Details
    ISSN: 1432-2218
    Keywords: Laparoscopic ; Cholecystectomy ; Pregnancy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Although pregnancy was initially considered an absolute contraindication to laparoscopic cholecystectomy, there have been several case reports of successful laparoscopic cholecystectomy in pregnant patients in the literature over the past 4 years. We report our experience with six patients managed successfully with laparoscopic cholecystectomy during pregnancy. Methods: More than 1,300 laparoscopic cholecystectomies were performed by the Norfolk Surgical Group between May 1991 and June 1994. Six of these patients (∼0.5%) were operated on during pregnancy. We reviewed the management and operative technique used in these patients compared to our standard approach. The available literature was reviewed to identify any other factors which might be helpful in the management of these patients. Results: In this series we were able to perform laparoscopic cholecystectomy successfully in all six patients in whom it was attempted, with an overall course similar to that of nonpregnant patients. There were no significant complications to the patient or the fetus. All six patients have delivered healthy children and continue to do well. Discussion: With the addition of our 6 patients, there have been 32 successful laparoscopic cholecystectomies during pregnancy reported in the English literature. We feel laparoscopic cholecystectomy can be performed safely in pregnant patients and should be considered in any patient who presents with symptomatic cholelithiasis during pregnancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00187379
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Regulated production of recombinant echistatin by yeast (1990)
    Springer
    Biotechnology letters 12 (1990), S. 879-884 
    Details
    ISSN: 1573-6776
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The α-mating factor pre-pro-leader sequence under the regulation of theGAL10 promoter was used to direct the secretion of echistatin by recombinant yeasts. Optimization of the culture medium and host strain increased the productivity of shake flask cultures twenty-fold to 8 mg/L. In fermentors, the production of echistatin was greater than 40 mg/L.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01022583
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  • 8
    Electronic Resource
    Electronic Resource
    Graphs with prescribed degree sets and girth (1981)
    Springer
    Periodica mathematica Hungarica 12 (1981), S. 261-266 
    Details
    ISSN: 1588-2829
    Keywords: Primary 05C38 ; Secondary 05C35 ; (r, n)-cage ; complete bipartite graph ; n-cycle ; degree set ; girth ; order of a graph ; vertex
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract For a finite nonempty set of integers, each of which is at least two, and an integern ≥ 3, the numberf( ;n) is defined as the least order of a graph having degree set and girthn. The numberf( ;n) is evaluated for several sets and integersn. In particular, it is shown thatf({3, 4}; 5) = 13 andf({3, 4}; 6) = 18.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01849614
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