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  • 1
    Electronic Resource
    Electronic Resource
    Interleukin-6-Mediated Autocrine Growth Promotion in Human Glioblastoma Multiforme Cell Line U87MG (1998)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 71 (1998), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Human glioblastoma multiforme cell lines, brain tumor biopsy tissue, and normal human fetal brain synthesize interleukin (IL)-6 and IL-6 receptor (IL-6R). Neither of these is expressed in human neurons or neuroblastoma cell lines in culture. Astrocytes from fetal brain grown in culture retain the ability to synthesize IL-6 but do not express IL-6R as inferred from RT-PCR and Southern blot studies. Coexpression of IL-6 and IL-6R in the glioblastoma cell line U87MG is confirmed by immunofluorescence staining. Both specific monoclonal antibodies against IL-6 and IL-6R and antisense oligonucleotide to IL-6 mRNA inhibit the growth of U87MG cells in culture, suggesting the existence of a functional autocrine growth loop. Anti-IL-6 antibodies also inhibit the growth of glioblastoma cell lines U373 and U118. The expression of IL-6 by human fetal astrocytes in culture is highly suggestive of its role as an oncofetal protein responsible for rapid proliferation of fetal and tumor cells but not cells of adult brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1998.71051837.x
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  • 2
    Electronic Resource
    Electronic Resource
    Dehydrochlorinated poly(vinyl chloride)-g-polystyrene. II. Characterization and physical properties (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 28 (1983), S. 1283-1298 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Dehydrochlorinated poly(vinyl chloride)-g-polystyrene (DHPVC-g-PSt) prepared by free radical grafting was characterized, and some of its physical properties were evaluated. The presence of graft was established by the appearance of new absorption peaks in the IR spectra of the graft copolymer. GPC analysis showed increase in the average molecular weights of the graft copolymer upon increase in the PSt content. Besides, GPC revealed the uniform PSt distribution of DHPVC-g-PSt. A marked improvement in the thermal stability of DHPVC-g-PSt over that of DHPVC and DHPVC/PSt blends was observed. Graft copolymers with high percent grafting were thermally more stable than even the original PVC. Stress-strain data indicated decrease in yield stress, breaking stress and elongation, along with an increase in the initial modulus, upon increase in PSt content of the graft copolymer.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1983.070280403
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  • 3
    Electronic Resource
    Electronic Resource
    Dehydrochlorinated poly(vinyl chloride-g-styrene). I. Effect of synthesis conditions (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 28 (1983), S. 1245-1254 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Dehydrochlorinated poly(vinyl chloride) (DHPVC) was graft copolymerized with styrene monomer using benzoyl peroxide (Bz2O2) as free radical initiator, in vacuum. The effect of synthesis conditions such as time, initiator concentration, the ratio of monomer to polymer, and temperature on various grafting parameters was studied. On the whole, a maximum of 47 wt % polystyrene (PSt) in the graft (DHPVC-g-PSt) was obtained. PSt contents of graft copolymers determined by gravimetry, chlorine analysis, and UV spectroscopy have been compared. A “grafting from” mechanism has been proposed for the graft copolymerization.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1983.070280328
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  • 4
    Electronic Resource
    Electronic Resource
    Photoinduced graft copolymerization of nylon 6 fibers with acrylamide. I. Effect of synthesis conditions (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 28 (1983), S. 2125-2129 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1983.070280624
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  • 5
    Electronic Resource
    Electronic Resource
    Photoinduced graft copolymerization of nylon 6 fibers with acrylamide. II. Characterization and evaluation of properties (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 28 (1983), S. 2217-2226 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Nylon 6-g-polyacrylamide graft copolymer prepared by photoinduced initiation was characterized and some of its properties were evaluated. Intrinsic viscosity of the graft copolymer increased continously with percent grafting. Thermal stability decreased corresponding to the increase in add-on %. The moisture regain, diameter, and density showed an increase with percent grafting. The acid dyeability of the graft copolymer decreased with increase in graft level, whereas the disperse dye uptake increased initially up to a graft add-on of 28.9% and then showed a decrease.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1983.070280708
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