ISSN:
1432-1920
Keywords:
Gadolinium-DTPA
;
Magnetic resonance imaging
;
Neoplasm
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We retrospectively reviewed the findings in 655 consecutive young patients who underwent contrastenhanced MR examinations (1.5T) of the head or spine. Their ages ranged from 4 months to 20 years (mean 10 years). There was a 1.7% incidence of minor adverse reactions to gadolinium (Gd)-DTPA, none of which required treatment; no serious adverse reactions were encountered. Based on the radiologic diagnosis the patients were divided into three groups: (1) normal, (2) CNS neoplasm, (3) abnormal but not neoplasm. There were 178 patients thought to have CNS neoplasms and of these 156 (88%) enhanced. Of 124 histologically confirmed neoplasms 115 (93%) showed enhancement after Gd-DTPA. Eight children had histologically confirmed spinal neoplasms; 5 of 6 neurofibromas and 2 ependymomas enhanced. In the 216 patients with abnormalities thought not to be neoplastic, the enhancement rate was 11%; most of the enhancing lesions were vascular malformations. There were very few examples of inflammatory disease, acute trauma or stroke among our patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00588157
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