ISSN:
1432-1351
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Responses of single labellar sugar receptors to glucose and its derivatives related to C1 were studied in the fleshfly, Boettcherisca peregrina. Analyzing concentration-response curve with each stimulant, we estimated its affinity for the sugar receptor site, the maximum response it evoked, and the Hill coefficient (Table 1). The results showed: (1) a polar group such as −OH both in α and β position was not necessary for stimulation; (2) α-glucose had the same affinity, but larger maximum response and smaller Hill coefficient in comparison with β-glucose; (3) a polar group such as ethylene glycol residue in α position was favorable for both affinity and the maximum response; (4) non-polar groups such as methyl, ethyl and p-nitrophenyl groups in α position were favorable for the affinity but not for the maximum response, whereas the same in β position were unfavorable both for the affinity and for the maximum response; (5) derivatives with β-configuration showed a tendency to give the concentration-response curve of higher Hill coefficients than those with α-configuration.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00395503
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