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  • 1
    ISSN: 1432-1173
    Keywords: Schlüsselwörter: UV-Strahlung – Biopositive Effekte – Hypercholesterinämie – Kreislauffunktionen – Serumparameter ; Key words: UV radiation – Biopositive effects – Hypercholesterolaemia – Blood circulation functions – Serum parameters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract. During a period of 3 years, four controled clinical studies in 34 patients with hypercholesterolaemia and 40 healthy persons – in some cases with stratification of the basic cholesterol levels and matched pair formation – were performed to find out the effects of serial sun-like UV irradiation on various serum parameters and blood circulation functions. The following significant effects were observed. Patients with hypercholesterolaemia: increase of HDL cholesterol after termination of the serial UV irradiation, increase of serum 25 (OH)D3 levels, decrease of serum triiodothyronine, decrease of serum lactate; healthy persons: decrease of resting pulse rate, decrease of recovery pulse rate, decrease of systolic blood pressure. All effects were induced by application of suberythematous UV doses, i.e. amounts of UV with a relatively low risk of side effects.
    Notes: Zusammenfassung. Über einen Zeitraum von 3 Jahren wurden von uns an 34 Patienten mit Hypercholesterinämie und 40 Gesunden jeweils in den Monaten November bis März 4 kontrollierte klinische Studien – teilweise unter Stratifizierung der Cholesterinausgangswerte und matched pair Bildung – zur exakten Erfassung der Wirkungen serieller sonnenlichtähnlicher UV-Bestrahlungen auf Serum- und Kreislauffunktionsparameter durchgeführt. Gegenüber Bestrahlungen mit sichtbarem Licht konnten von uns folgende signifikante Efekte der UV-Strahlung festgestellt werden: Hypercholesterinämiepatienten: HDL-Erhöhung nach Bestrahlungsende, 25 (OH)D3-Anstieg im Serum; Trijodthyronin-Abfall im Serum. Laktatabfall im Serum Gesunde: Abfall der Ruhepulsfrequenz; Abfall der Erholungspulsfrequenz; Senkung des systolischen Blutdrucks. Alle Effekte waren durch Einstrahlung suberythematöser UV-Dosen, also mit einem für die Haut vertretbaren Bestrahlungsrisiko, auslösbar.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-5233
    Keywords: Fractional catabolic rate of endogenous triglycerides ; Free fatty acids (FFA) ; Glucose ; Insulin ; Triglycerides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In non-diabetic persons whose serum triglyceride (TG) concentrations ranged from normal to very high levels, endogenous TG turnover was measured using the radioglycerol method of Farquhar and coworkers. Insulin, FFA, and glucose concentrations were estimated during an oral glucose tolerance test. Stimulated insulin levels were correlated positively to TG concentrations and absolute TG turnover rates, and negatively to fractional TG catabolic rates. FFA concentrations had similar relationships, also in non-insulin-dependent diabetics. A more detailed analysis showed that elevated insulin and FFA levels — as an expression of peripheral insulin resistance — are a typical finding in the kind of patients whose fractional TG catabolic rate is low [≤0.210 (h−1)], irrespective of actual serum TG concentration. Our data do not suggest a stimulatory role of insulin for TG production.
    Type of Medium: Electronic Resource
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