Electronic Resource
Palo Alto, Calif.
:
Annual Reviews
Annual Review of Physical Chemistry
52 (2001), S. 71-92
ISSN:
0066-426X
Source:
Annual Reviews Electronic Back Volume Collection 1932-2001ff
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
Abstract The atomic force microscope operates on surfaces. Since surfaces occupy much of the space in living organisms, surface biology is a valid and valuable form of biology that has been difficult to investigate in the past owing to a lack of good technology. Atomic force microscopy (AFM) of DNA has been used to investigate DNA condensation for gene therapy, DNA mapping and sizing, and a few applications to cancer research and to nanotechnology. Some of the most exciting new applications for atomic force microscopy of DNA involve pulling on single DNA molecules to obtain measurements of single-molecule mechanics and thermodynamics.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1146/annurev.physchem.52.1.71
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