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  • 1
    ISSN: 1432-0509
    Keywords: Key words: Exocrine pancreatic tumor—Endocrine pancreatic tumor.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Our purpose was to review a series of 14 patients with atypical exocrine and endocrine pancreatic tumors to derive characteristic computed tomographic and pathologic features that might allow better diagnosis, categorization, and management of these patients. Methods: Medical records from several university medical centers were reviewed retrospectively. Results: We identified three separate types of pancreatic tumors that had substantially different morphologic and prognostic features. Among these rare tumors, anaplastic carcinoma was the most common (nine of 14 cases), and these tumors were large, partly necrotic, locally invasive, and invariably metastatic (lymph nodes and/or liver) at the time of diagnosis. Three patients with poorly differentiated (small cell) carcinoma had a confluent pancreatic mass and lymphadenopathy but no ductal obstruction, closely resembling lymphoma or metastatic disease. Two patients with giant cell (osteoclastlike) carcinoma had a large, encapsulated multicystic tumor with hemorrhage, and these tumors were resectable for cure. Conclusion: Although a specific diagnosis may not be possible in some cases, we believe that knowledge of certain pathologic and computed tomographic features should lead to optimal diagnosis, therapy, and prognosis.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0509
    Keywords: Key words: Abdomen, magnetic resonance—Liver, magnetic resonance—Magnetic resonance, rapid imaging—Magnetic resonance, diffusion study—Magnetic resonance, echo planar.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: To determine the potential ability of diffusion-weighted magnetic resonance (MR) imaging with single-shot echo-planar imaging (DW imaging) in the upper abdomen by apparent diffusion coefficient (ADC) and signal:intensity ratio (SIR) measurements. Methods: DW imaging was performed in 61 clinical patients. ADCs in the liver, pancreas, spleen, kidney, and different pathological conditions were calculated. Spleen-to-liver SIR and segmental intensity difference of the liver (SID) were also calculated. Results: The mean ADCs (mm2/s) were 2.28 × 10−3± 0.07 in the liver, 1.44 × 10−3± 0.05 in the spleen, 1.94 × 10−3± 0.19 in the pancreas, and 5.76 × 10−3± 0.06 in the kidney. The mean ADC of cirrhotic liver was 1.96 × 10−3± 0.62, which was lower than that of normal liver. Other pathologic conditions also showed ADCs different from those of normal tissues. All DW images showed significantly higher spleen-to-liver SIRs and SIDs than did T2-weighted images (p 〈 0.05). Conclusion: The mean ADCs obtained with DW imaging were different in each upper abdominal organ and with each pathologic condition. DW images showed better soft tissue contrast than did T2-weighted images with regard to SIR and CNR in depicting and characterizing upper abdominal disorders.
    Type of Medium: Electronic Resource
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