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Determination of Troponin I Release After CABG Surgery (2005)

Noora, Joseph ; Ricci, Christopher ; Hastings, Deborah ; [et al.]

350 Main Street , Malden , MA 02148-5020 , USA and 9600 Garsington Road , Oxford OX4 2XG , England . : Blackwell Science Inc

Journal of cardiac surgery 20 (2005), S. 0

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ISSN: 1540-8191

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Abstract Background: Troponin I is used to diagnose myocardial infarction (MI). Its use and pattern of elevation is not well defined in coronary artery bypass graft (CABG) surgery. This study assessed the timing of troponin I elevation in patients undergoing urgent CABG. Method: Patients undergoing urgent isolated-CABG with cardiopulmonary bypass were studied prospectively. Blood samples were taken to measure CK, CK-MB, and troponin I: preoperatively, 7 hours postoperatively, 14 to 18 hours postoperatively, 30 to 48 hours postoperatively, and on postoperative day 4. Electrocardiograms and in-hospital course were recorded. Perioperative MI (PMI) was defined by either (i) ECG criteria of new Q-waves in the presence of CK-MB elevation 〉50 μg/L or (ii) CK-MB 〉 100 μg/L. Results: Of the 50 patients studied, 6 met the criteria for PMI (12%); 2 by criteria (i) and 4 by criteria (ii). In patients not meeting the criteria for MI the troponin I level peaked at 7 hour post-op with a mean of 20.97 μg/L (95% CI, 17.11 to 24.83). At this time, patients who met the criteria for MI had a mean troponin I level of 46.85 μg/L (95% CI, 36.40 to 57.30). Of variables investigated for the 44 patients who did not meet MI criteria, only preoperative troponin I level impacted peak postoperative troponin I. Conclusions: CABG elevates troponin I far beyond current diagnostic benchmarks without the clinical occurrence of a MI and appears to peak during the second postoperative day. An elevated preoperative troponin I may predict an elevated peak postoperative troponin I in patients who do not have a PMI.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.0886-0440.2005.200387.x

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Shoplifting in Retail Clothing Outlets:: An Exploratory Research (1994)

Lin, Binshan ; Hastings, Deborah Ann ; Martin, Christopher

Bingley : Emerald

International journal of retail and distribution management 22 (1994), S. 24-29

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ISSN: 0959-0552

Source: Emerald Fulltext Archive Database 1994-2005

Topics: Economics

Notes: Presents a report of the study about shoplifting problems in retailclothing outlets which was carried out during the autumn of 1993, withthe primary purpose of examining managers' attitudes towards shopliftingin some detail and the secondary purpose of identifying copingstrategies that can be used by retailing managers to deal withshoplifting. Investigates four crucial issues: layout design, magnitudeof the problem, prosecution efforts and detection and preventionconsiderations. Includes recommendations and implications based on asurvey taken to help retailers with their shoplifting problems.