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  • 1
    Electronic Resource
    Electronic Resource
    GABAergic synapses of the suprachiasmatic nucleus exhibit a diurnal rhythm of short-term synaptic plasticity (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 19 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We examined synaptic plasticity at intrasuprachiasmatic nucleus (SCN) γ-aminobutyric acid (GABA)ergic synapses by measuring the paired-pulse ratio between pairs of evoked inhibitory postsynaptic currents (IPSCs). Interstimulus intervals were chosen to represent the range of spontaneous action potential firing frequencies found in SCN neurons. A majority of synapses studied during the day exhibited paired-pulse depression (PPD), whereas a majority of synapses studied during the night showed no PPD. Two types of PPD were found. Type 1 PPD expresses the greatest inhibition at shorter interstimulus intervals, is predominant in the early morning and is likely to be a result of vesicle depletion. Type 2 showed the greatest inhibition at interstimulus intervals between 175 and 225 ms, is found throughout the day yet rarely at night and is likely to be a result of a Ca2+-dependent mechanism that is independent of pertussis toxin-sensitive G-proteins. Thus, multiple mechanisms of synaptic plasticity modulate intra-SCN communication throughout the diurnal cycle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03382.x
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  • 2
    Electronic Resource
    Electronic Resource
    Khennas, Smail: Industrialization, Mineral Resources and Energy in Africa : Oxford, 1992 (1995)
    Cambridge : Cambridge University Press
    The @journal of modern African studies 33 (1995), S. 503-506 
    Details
    ISSN: 0022-278X
    Source: Cambridge Journals Digital Archives
    Topics: Ethnic Sciences , History , Political Science , Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0022278X00021248
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  • 3
    Electronic Resource
    Electronic Resource
    Morbus Pringle (1961)
    Springer
    Archives of dermatological research 213 (1961), S. 876-877 
    Details
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588892
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  • 4
    Electronic Resource
    Electronic Resource
    Fibrosarcoma in infants and children: a retrospective analysis – overdiagnosis in earlier years (1999)
    Springer
    Pediatric surgery international 15 (1999), S. 123-128 
    Details
    ISSN: 1437-9813
    Keywords: Key words Fibrosarcoma ; Infancy and childhood ; Fibrosarcoma of mesentery and retroperitoneum ; Pathohistology ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract During a 30-year period, 22 patients considered to have a fibrosarcoma (FS) were treated. In a retrospective study the clinicopathologic findings were summarized. With histologic and immunohistochemical re-evaluation, the diagnosis was confirmed in 8 cases. For 6 further patients FS was very probable but specimens were not available. In 8 cases the diagnosis was revised and benign lesions were found in 7. Two patients with irresectable tumors died (infantile FS, FS of mesentery and retroperitoneum). After repeated local recurrences and spread on the affected extremity, an amputation was life-saving in 1 boy. In earlier years many tumors were classified as FSs. Today, immunohistochemistry and molecular-biological methods are valuable tools to clearly identify these tumors. Wide local excision or en-bloc resection without sacrificing any significant function of the part should be the primary form of treatment in infants. Primary re-excision after incomplete excision should have priority over any adjuvant treatment. Preoperative chemotherapy may avoid incomplete resection or mutilation in cases with extended congenital FS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003830050532
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  • 5
    Electronic Resource
    Electronic Resource
    Cross-Sectional Profitability of Namibian Formal Small-Scale Mining Firms in 1990 (1998)
    Springer
    Small business economics 11 (1998), S. 57-73 
    Details
    ISSN: 1573-0913
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract Namibia considers formal small-scale mining firms (FSSMFs) as an important part of the solution to the problems of high unemployment, poverty, and the diminishing role of large-scale mining firms facing the country. However, to be a solution FSSMFs must be profitable first. This paper examines and presents simple estimates and tests of the probability of 25 Namibian SSMFs being profitable. The results suggest that in terms of productivity, specialization, size and structure, small is not as beautiful as generally presented. The findings recommend capital formation and competitive diversification of production and products.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007951618353
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  • 6
    Electronic Resource
    Electronic Resource
    No enhancement of fusion probability by the neutron halo of 6 He (2004)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 431 (2004), S. 823-826 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Quantum tunnelling through a potential barrier (such as occurs in nuclear fusion) is very sensitive to the detailed structure of the system and its intrinsic degrees of freedom. A strong increase of the fusion probability has been observed for heavy deformed nuclei. In light exotic nuclei such ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature02984
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  • 7
    Electronic Resource
    Electronic Resource
    Ein Beitrag zur Methodik des Salmonella-Nachweises im Abwasser, Flußwasser und Schlamm (1959)
    Springer
    Medical microbiology and immunology 145 (1959), S. 529-542 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es wird über eineinfaches Anreicherungsverfahren zum Nachweis von Salmonellen im Abwasser, Flußwasser und Schlamm berichtet, das im Rahmen von Untersuchungen zur Frage der Eliminierung dieser Mikroorganismen aus Abwässern durch den Klärvorgang entwickelt wurde. Das Verfahren basiert nach dem Vorbild des Eijkman-Prinzips auf einer zehnfach konzentrierten Nährlösung und gestattet, wie die vorgelegten Untersuchungsergebnisse belegen, bei verhältnismäßig geringem Arbeits- und Materialaufwand eine relativ große Ausbeute, die es somit besonders für den Routinebetrieb brauchbar erscheinen läßt. Zur quantitativen Bestimmung der Salmonella-Belastung einer Wasser- oder Schlammprobe kann mit diesem Verfahren einSalmonella-Titer ermittelt werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02156381
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  • 8
    Electronic Resource
    Electronic Resource
    Die in vitro-Empfindlichkeit des Bacteroides melaninogenicus gegen die gebräuchlichen Antibiotica und Sulfonamide (1959)
    Springer
    Medical microbiology and immunology 146 (1959), S. 1-7 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es wird ein Überblick Über die invitro-Empfindlichkeit desBacteroides melaninogenicus gegen die derzeit gebräuchlichen Antibiotica und Sulfonamide gegeben, die im Plattentestverfahren an Hand einer Serie von 35 Stämmen verschiedener Herkunft (Mensch und Tier) ermittelt wurde. Mit Ausnahme von Streptomycin, Chloramphenicol, Selectomycin und Polymyxin B erwiesen sich alle Mittel innerhalb ihrer erreichbaren Blutspiegelwerte gegenÜber sämtlichen B.m.-Stämmen als gut wirksam. Der Blättchentest als einfaches Routineverfahren ist fÜr Sensibilitätsbestimmungen des B.m. nicht brauchbar.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02162053
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  • 9
    Electronic Resource
    Electronic Resource
    Infektionsversuche an Laboratoriumstieren und in vitro-Untersuchungen zur Fermentausstattung des Bacteroides melaninogenicus (1960)
    Springer
    Medical microbiology and immunology 146 (1960), S. 341-349 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung In Ergänzung unseres ersten Beitrages wird über Infektionsversuche mit Reinkulturen des Bacteroides melaninogenicus an Kaninchen, Meerschweinchen und weißen Mäusen berichtet. Während es bei Kaninchen und Meerschweinchen gelang, eine schwere nekrotisierende Gangrän mit Septicopyämie hervorzurufen, erwies sich die weiße Maus diesem Bacterium gegenüber als refraktär. Weiterhin war es möglich, für die Pathogenität des Bacteroides melaninogenicus bedeutsame Fermente im Sinne von Hämotoxinen, proteolytischen Enzymen, Plasmacoagulasen und Fibrinolysinen nachzuweisen. Gewebsaufschließende Fermente, wie Hyaluronidasen usw., scheint dieser Mikroorganismus nach früheren Untersuchungen unseres Instituts (Brede) nicht zu entwickeln.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02152262
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  • 10
    Electronic Resource
    Electronic Resource
    Über den Nachweis des Bacteroides melaninogenicus in Krankheitsprozessen bei Mensch und Tier (1960)
    Springer
    Medical microbiology and immunology 146 (1960), S. 331-340 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Im vorliegenden Beitrag wird über 621 Krankheitsfälle desMenschen berichtet, an denen der Bacteroides melaninogenicus beteiligt war. Wie die Auswertung dieses umfangreichen Untersuchungsmaterials ergab, scheint der Bacteroides melaninogenicus nur selten als Krankheitserreger sui generis aufzutreten. Er ist aber fraglos imZusammenwirken mit anderen fakultativ-pathogenen Mikroorganismen an der Genese der sogenanntenfötiden Entzündungsprozesse beteiligt. In diesem Zusammenhang wird auf die Affinität dieses Bacteriums zu anderen Vertretern des„Anaeroben Kollektivs“, insbesondere anaeroben bzw. mikroaerophilen Streptokokken, Fusobakterien und Leptotrichia, hingewiesen. Analog den menschlichen Krankheitsprozessen kommt der Bacteroides melaninogenicus auch in Infektionen vonTieren vor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02152261
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