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  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To evaluate the reproducibility of the clinical judgement of gynaecologists, gynaecologists in training and gynaecologic oncologists and to compare the predictive performance of the offhand assessment with the predictive performance of existing mathematical models for the pre-operative assessment of the adnexal mass.Design Questionnaire with paper cases of women operated on for an adnexal mass.Setting Gynaecological unit in a teaching hospital in the South of The Netherlands.Population Women who underwent surgery for adnexal mass between January 1991 and December 1998.Methods We offered 45 gynaecologists five different sets of 34 cases, with data on female age and menopausal status, a written description of the sonography, Doppler flow measurement and serum CA125 measurement. Nine observers for every set were asked to estimate the probability of malignancy.Main outcome measures The reproducibility of the risk estimates as made by the participants was expressed with an intraclass correlation coefficients. The accuracy of the judgement of the clinicians and the result of mathematical models in the prediction of malignancy were expressed with sensitivity, specificity, and receiver-operating characteristic curves.Results Neither clinically relevant nor statistically significant differences could be found between the accuracy of the risk assessments made by the clinicians and the accuracy of the risk assessments made by prediction models.Conclusion This study demonstrates that at this moment there is no need to introduce complicated predictive scoring systems such as neural networks or logistic regression models for the pre-operative assessment of the adnexal masses.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Sozial- und Präventivmedizin 14 (1969), S. 119-125 
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die vorliegende Arbeit diskutiert methodologische Probleme der «multivariate analysis», Kausalanalyse, Systemanalyse und Interaktionsanalyse. Es werden einige neue Techniken vorgeschlagen, so die eines prädiktiven Modelles, das mehrere unabhängige Variablen mit einer abhängigen verbindet (H. Scolnik); der systematische Vergleich zwischen gleichzeitigen und zeitlich gestaffelten Korrelationen von «panel»-Daten (Pelz und Andrews); die Analyse gleichzeitiger Assoziationen auf Grund der Bewegungen von Einheiten innerhalb und außerhalb des Musters; die Systemanalyse im Sinne der Herstellung eines «fits», eines Modelles von miteinander zusammenhängenden und formalisierten Propositionen, und der Interpretation des angepaßten Modelles mit Hilfe einer Systemtheorie; und die Interaktionsanalyse, die sich mit strukturellen Chancen befaßt, welche sich aus der Besetzung eines Feldes durch Einheiten ergibt. Alle diese Techniken hängen miteinander zusammen und spiegeln denselben Trend zur Überprüfung von Kausalpropositionen wider.
    Type of Medium: Electronic Resource
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