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  • 1
    Electronic Resource
    Electronic Resource
    Environmental stresses and mobilization of transposable elements in inbred lines of Drosophila melanogaster
    Amsterdam : Elsevier
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 248 (1991), S. 51-60 
    Details
    ISSN: 0027-5107
    Keywords: Chemical treatment ; Drosophila melanogaster, inbred line ; Heat shock ; Transposable elements
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0027-5107(91)90087-5
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  • 2
    Electronic Resource
    Electronic Resource
    Die Gewinnung von Substanz P aus der Proteolipidfraktion von Hirngewebe (1966)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 253 (1966), S. 44-44 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00259246
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  • 3
    Electronic Resource
    Electronic Resource
    Massive changes in genomic locations of P elements in an inbred line ofDrosophila melanogaster (1990)
    Springer
    Naturwissenschaften 77 (1990), S. 485-488 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01135928
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  • 4
    Electronic Resource
    Electronic Resource
    Der Einfluß injizierter Aminopeptidasen und von Carboxypeptidase auf die Blutdruckwirkung von Angiotensin (1965)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 250 (1965), S. 264-265 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00258601
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  • 5
    Electronic Resource
    Electronic Resource
    Beeinflussung der Blutdruckwirkung von Angiotensin durch Aminopeptidasen und Carboxypeptidase (1965)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 251 (1965), S. 28-38 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. The pressor effect of angiotensin II was reduced after intravenous injections or infusions in spinal cats of several aminopeptidases and carboxypeptidase A. 2. The short half life of the enzymes in cats was the reason of the relatively transient effect. The half life of leucine aminopeptidase (LAP) and aminopeptidase from pig kidneys (AP-M) was 4–6 min, of carboxy-peptidase A 50–80 min and of aminopeptidase from aspergillus (AP-Asp.) 10–20 min. 3. The increase of enzyme concentrations in the blood of cats was in correlation with the decrease of the angiotensin pressor effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00245727
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  • 6
    Electronic Resource
    Electronic Resource
    Substanz P in der Retina (1966)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 253 (1966), S. 246-259 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. The substance P content of cow retinae has been estimated by comparing the extract from the retina with two different standard preparations (SP-S, SP-B) extracted from cow gut. The bioassay on various preparations (guinea-pig ileum, rat duodenum, hen coecum, rabbit blood pressure) gave different substance P equivalents. The standards prepared from the gut are therefore of limited sufficiency for estimating substance P in nervous tissue. The substance P content of retina was not altered by environmental light. 2. Both substance P standards (SP-S, SP-B) contained several active fractions after separation by paper- and column chromatography. The retina extract contained only one fraction corresponding to Zetler's fraction Fa. 3. The highest substance P content per mg protein has been found in the subfraction M2 which also contained the highest concentration of cholineacetylase when subcellular particles have been separated according to the method of Whittaker. 4. Separation of subcellular particles of the retina by the de Robertis method showed the highest smooth muscle stimulating activity in the “synaptic vesicle fraction” M2. The slow type of contraction produced by this fraction, however, differed from the faster type of contraction produced by the standards or the brain extracts containing substance P.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00246375
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  • 7
    Electronic Resource
    Electronic Resource
    Die Gewinnung von Substanz P aus dem Lipidextrakt von Hirngewebe (1966)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 253 (1966), S. 265-279 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00246377
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Der Einfluß von Lithiumchlorid auf die Blutdruckwirkung von Renin, Angiotensin und Noradrenalin bei Ratten (1967)
    Springer
    Journal of molecular medicine 45 (1967), S. 659-660 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The blood pressure effect of angiotensin and renin is strongly decreased in rats treated with lithiumchloride, the effect of norepinephrine is only little diminished. In the aorta stripe preparation of lithium treated rats a reduced contraction by angiotensin is also observed. The contraction by norepinephrine is equal compared with the control group. The results demonstrate the influence of intracellular sodium concentration in the smooth vascular muscles for the blood pressure effect of angiotensin.
    Notes: Zusammenfassung Bei Ratten ist nach Lithiumverabreichung die Blutdruckwirkung von Angiotension und Renin stark, die von Noradrenalin nur gering abgeschwächt. Am isolierten Aortenpräparat von lithiumvorbehandelten Ratten ist die durch Angiotensin ausgelöste Kontraktion ebenfalls deutlich, die Kontraktion nach Noradrenalin dagegen gegenüber der Kontrollgruppe nur gering vermindert. Die Befunde sprechen dafür, daß die Blutdruckwirkung von Angiotensin von der Natriumkonzentration in der glatten Muskelzelle abhängig ist.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01747195
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  • 9
    Electronic Resource
    Electronic Resource
    Zur Regulation der Reninsekretion durch Angiotensin (1967)
    Springer
    Journal of molecular medicine 45 (1967), S. 657-659 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In 6 out of 11 normotensive humans renin activity in peripheral venous plasma is decreased by 40% of the praeinfusion level after an angiotensin infusion continuing 30–60 minutes and raising diastolic blood pressure by 20 mm Hg. In 4 out of 8 patients with secondary aldosteronism or adrenal insufficiency and 4 out of 16 hypertensive patients plasma renin activity is increased by angiotensin infusion. Norepinephrine in pressor doses causes in part a decrease of plasma renin activity in patients with secondary aldosteronism or adrenal insufficiency and an increase in the normotensive and hypertensive groups. The negative feed back mechanism between angiotensin level in bloodplasma and renin secretion is discussed.
    Notes: Zusammenfassung Die Reninaktivität im peripheren Venenblut sinkt nach einer intravenösen Infusion von Angiotensin in Dosen, die für 30–60 min einen diastolischen Blutdruckanstieg von 20 mm Hg aufrechterhalten, bei 6 von 11 Gesunden um mehr als 40% der Ausgangswerte ab. Bei 4 von 8 Patienten mit sekundärem Aldosteronismus oder M. Addison sowie 4 von 16 Hochdruckkranken führt Angiotensin dagegen zu einem Anstieg des Plasmarenins bis auf das Doppelte. Nach einer pressorischen Noradrenalin-infusion ist die Plasmareninaktivität beim sekundären Aldosteronismus und M. Addison vermindert, bei Gesunden und Hochdruckkranken erhöht. Die Befunde werden in bezug auf einen direkten negativen Rückkoppelungsmechanismus zwischen Angiotensinkonzentration im Blut und Reninsekretion erörtert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01747194
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  • 10
    Electronic Resource
    Electronic Resource
    Substanz P-Gehalt und Capillarpermeabilität in Extrakten aus Substantia nigra (1966)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 253 (1966), S. 260-264 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. A correlation between smooth muscle stimulating activity and capillar permeability increasing activity of brain extracts has previously been found, whereby substantia nigra extracts showed highest activity. Subfractions of substantia nigra extracts have been used to find further evidence wether both effects are caused by the same factor. 2. Fractionation on aluminium oxide column by Zetlers method reveal three peptide fractions (Fa, Fb, Fc). Only in fractions of Fb the smooth muscle activity and permeability effect were found, exactly in the same distribution; no activity was present in other fractions. These findings further support the assumption that the permeability effect is due to the smooth muscle contracting factor, i.e. substance P.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00246376
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