ISSN:
1573-904X
Keywords:
mass spectrometry
;
fast atom bombardment
;
peptide analysis
;
protein analysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The techniques of fast atom bombardment mass spectrometry has overtaken (but not entirely replaced) field desorption mass spectrometry as the method of choice for the analysis of nonvolatile, thermally labile polar compounds. The ease with which information may be obtained on a wide variety of molecules is a result of the relative simplicity of the technique. A brief history of bioorganic mass spectrometry leading to the development of fast atom bombardment is presented, as well as a description of the method and ancillary techniques. Selected examples of its application to peptide and protein structural problems attest to the power and utility of fast atom bombardment mass spectrometry.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1016465507903
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