ISSN:
1434-0879
Keywords:
Bacteriuria
;
Urinary tract infection
;
Neurogenic bladder
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Bacteriuria and associated renal damage is common in children with a neurogenic bladder, but the pathogenesis of urinary tract infection (UTI) is undefined. We examined the association between periurethral bacterial colonization and the presence of urinary leukocytes in 76 catheter urine specimens from children with neurogenic bladders. Although all the children were asymptomatic, 38/76 (50%) of the urine cultures were positive. Periurethral colonization was significantly more common with positive than with negative urine cultures, suggesting a pathogenetic role for periurethral bacteria in infection of the neurogenic bladder. Urinary leukocytes were present in 24/38 (63%) with positive cultures, as against none (0/38) of those with negative urine cultures, and their presence represents a host response to bladder bacteriuria.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00922749
Permalink
